Najafizadeh K, Abbasi A, Ghorbani F, Radpei B, Kashani B S, Ahmadi Z H, Hamidinia S, Moghani-Lankarani M, Assari S, Velayati A A
Lung Transplantation Research Center, National Research Institute of TB and Lung Disease, Shaheed Beheshti Medical University, Tehran, Iran.
Transplant Proc. 2009 Sep;41(7):2723-5. doi: 10.1016/j.transproceed.2009.06.145.
The majority of transplantations depend solely on cadaveric organs. In recent years, special focus has been directed toward brain-dead patients in Iran, but it seems that there is limited information regarding the characteristics of cadaveric organ donation in our country.
This is a retrospective analysis of data of our Organ Procurement Unit (OPU), which is one of the most active organ procurement units in Iran. We incorporated the data on all organ donations from brain-dead patients between 2004 and 2008 into the present study. Demographic characteristics of the patients along with data regarding brain death and organ donation were extracted from already registered data on patients.
Among 93 brain-dead patients registered in the database of the OPU, organs were retrieved from 85% (n = 79). Out of the 14 patients from whom no organ was retrieved, the cause for this failure was death before donation in 85% (n = 12). The numbers of donated organs varied between zero and six (mean +/- standard deviation = 3.1 +/- 1.7). The most donated organs in terms of frequency and count were: right kidney (n = 68; 73.1%), left kidney (n = 67; 72%), liver (n = 63; 67.7%), heart (n = 40; 43%), pancreas (n = 5; 5.4%), and lung (n = 4; 4.3%).
The overall organ retrieval rate from brain-dead patients by this OPU was comparable to that of developed countries; however, we still believe we can improve this rate/scale.
大多数移植手术仅依赖尸体器官。近年来,伊朗特别关注脑死亡患者,但我国关于尸体器官捐赠特征的信息似乎有限。
这是对我国器官获取单位(OPU)数据的回顾性分析,该单位是伊朗最活跃的器官获取单位之一。我们将2004年至2008年间所有脑死亡患者的器官捐赠数据纳入本研究。患者的人口统计学特征以及脑死亡和器官捐赠数据从已登记的患者数据中提取。
在OPU数据库中登记的93例脑死亡患者中,85%(n = 79)的患者器官被获取。在14例未获取器官的患者中,85%(n = 12)的原因是在捐赠前死亡。捐赠器官的数量在0至6个之间(平均值±标准差 = 3.1±1.7)。按频率和数量计算,捐赠最多的器官依次为:右肾(n = 68;73.1%)、左肾(n = 67;72%)、肝脏(n = 63;67.7%)、心脏(n = 40;43%)、胰腺(n = 5;5.4%)和肺(n = 4;4.3%)。
该OPU从脑死亡患者中获取器官的总体比例与发达国家相当;然而,我们仍认为可以提高这一比例/规模。