[Mode of action of hypoglycemic sulfanilamides].
作者信息
Girardin E, Conte Devolx B
机构信息
Hôpital de jour d'Endocrinologie, Hôpital de la Conception, Marseille.
出版信息
Therapie. 1991 Jul-Aug;46(4):311-4.
PMID:1948807
Abstract
Sulfonylureas act as hypoglycemic agents by stimulating insulin secretion and improving insulin sensibility by a post-receptor mechanism. Their long term results mainly depend on extra-pancreatic mechanisms. Moreover they indirectly decrease triglyceridemia. Glipizide and gliclazide enhance fibrinolysis. Gliclazide also inhibits platelet aggregation and adhesion. The best indication of sulfonylureas is non insulin dependent diabetes with normal weight.
摘要
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