Maganha Carlos Alberto, Nomura Roseli Mieko Yamamoto, Zugaib Marcelo
Departamento de Obstetrícia e Ginecologia, Faculdade de Medicina, Universidade de São Paulo, São Paulo, SP.
Rev Assoc Med Bras (1992). 2009 Mar-Apr;55(2):169-74. doi: 10.1590/s0104-42302009000200021.
to study the relation between amniotic fluid volume and glycemic control in pregnancies complicated by diabetes mellitus type 1 and 2, followed in a specialized multidisciplinary prenatal care service.
This descriptive study was performed between January 2001 and December 2004. Inclusion criteria were: simple pregnancy, diagnosis of pregestational diabetes, beginning of prenatal care before the 26th week and absence of fetal anomaly. Cases with newborns small for gestational age were excluded. The amniotic fluid index (AFI) was measured weekly, beginning at the 27th week of gestation and continued until delivery and the maternal glycemic profile was obtained a week before ultrasound assessment. This profile consisted of the glycemic level averages and percentages of the abnormal high values. Correlation between the glycemic profile and the AFI was shown by the Spearman correlation test.
Sixty pregnant women were assessed and 659 correlations between the AFI and glycemic profile were obtained. No correlation was observed in any of the gestational weeks studied. The mean glycemic value was 103.69 mg/dl (SD=13.69) in the group with AFI pound18 cm, and the 103.67 mg/dl (SD=11.46) in the group with AFI < 18 cm and no significant difference was detected.
This study showed no correlation between AFI and maternal glycemic profile during the third trimester in type 1 and 2 diabetic pregnant women, undergoing standardized treatment and rigorous metabolic control.
在一家专业的多学科产前护理机构中，研究1型和2型糖尿病合并妊娠中羊水体积与血糖控制之间的关系。
本描述性研究于2001年1月至2004年12月进行。纳入标准为：单胎妊娠、孕前糖尿病诊断、孕26周前开始产前护理且无胎儿畸形。排除小于胎龄儿的病例。从妊娠27周开始每周测量羊水指数（AFI），直至分娩，并且在超声评估前一周获取孕妇血糖情况。该情况包括血糖水平平均值和异常高值的百分比。通过Spearman相关性检验显示血糖情况与AFI之间的相关性。
评估了60名孕妇，获得了AFI与血糖情况之间的659次相关性。在所研究的任何孕周均未观察到相关性。AFI≥18 cm组的平均血糖值为103.69 mg/dl（标准差=13.69），AFI<18 cm组的平均血糖值为103.67 mg/dl（标准差=11.46），未检测到显著差异。
本研究表明，在接受标准化治疗和严格代谢控制的1型和2型糖尿病孕妇的孕晚期，AFI与孕妇血糖情况之间无相关性。
