Department of Dermatology, Juntendo University School of Medicine, 2-1-1 Hongo, Bunkyo-ku, Tokyo, Japan.
Aesthetic Plast Surg. 2010 Apr;34(2):153-6. doi: 10.1007/s00266-009-9374-4. Epub 2009 Jun 2.
Benign symmetric lipomatosis, also known as Madelung disease, is a rare disorder characterized by fat distribution around the shoulders, arms, and neck in the context of chronic alcoholism. Complete excision of nonencapsulated lipomas is difficult. However, reports describing conservative therapeutic measures for lipomatosis are rare.
The authors present the case of a 42-year-old man with a diagnosis of benign symmetric lipomatosis who had multiple, large, symmetrical masses in his neck. Multiple phosphatidylcholine injections in the neck were administered 4 weeks apart, a total of seven times to achieve lipolysis.
The patient's lipomatosis improved in response to the injections, and he achieved good cosmetic results.
Intralesional injection, termed mesotherapy, using phosphatidylcholine is a potentially effective therapy for benign symmetric lipomatosis that should be reconsidered as a therapeutic option for this disease.
良性对称性脂肪瘤病,又称 Madelung 病,是一种罕见疾病,其特征是在慢性酗酒的情况下,脂肪分布在肩部、手臂和颈部周围。非包膜性脂肪瘤的完全切除较为困难。然而,关于脂肪瘤病保守治疗措施的报道较为少见。
作者报告了一例 42 岁男性良性对称性脂肪瘤病患者,其颈部存在多个大而对称的肿块。在 4 周的间隔时间内,分 7 次对颈部进行了多次卵磷脂注射,以实现脂肪分解。
注射后,患者的脂肪瘤病得到改善,并且获得了良好的美容效果。
使用卵磷脂的腔内注射,即脂肪内注射,是一种治疗良性对称性脂肪瘤病的有效方法,应重新考虑将其作为该疾病的一种治疗选择。