Eng T J
Kirurgisk avdeling, Buskerud sentralsykehus, Drammen.
Tidsskr Nor Laegeforen. 1991 Oct 20;111(25):3067.
The familial occurrence of Crohn's disease has attracted increasing interest. Among 32 cases of histologically verified Crohn's disease a sister and brother were found with clinical symptoms dating from the age of 15 and 18 years respectively. In both cases resection of the terminal ileum was performed to alleviate serious and acute gastrointestinal manifestations. Studies of the literature further emphasize the familial occurrence of Crohn's disease and the need for pertinent evaluation of family history in these patients.
克罗恩病的家族性发病已引起越来越多的关注。在32例经组织学证实的克罗恩病患者中,发现一对姐弟分别在15岁和18岁时出现临床症状。两例均行回肠末端切除术以缓解严重的急性胃肠道症状。对文献的研究进一步强调了克罗恩病的家族性发病以及对这些患者家族史进行相关评估的必要性。