[¹²⁵I粒子植入近距离治疗复发性腮腺恶性肿瘤]
[125I seed implant brachytherapy of recurrent parotid gland malignant tumor].
作者信息
Zhang Jie, Zhang Jian-Guo, Cai Zhi-Gang, Zhang Yi, Huang Min-Xian, Yu Guang-Yan
机构信息
Department of Oral and Maxillofacial Surgery, Peking University School and Hospital of Stomatology, Beijing 100081, China.
出版信息
Zhonghua Kou Qiang Yi Xue Za Zhi. 2009 Jan;44(1):2-4.
OBJECTIVE
To investigate the efficacy of radioactive seeds for the treatment of recurrence malignant parotid gland tumors.
METHODS
Thirty-three patients with recurrence malignant parotid gland tumor treated by radioactive seeds were retrospectively reviewed. Three patients received implanted radioactive seeds alone. Thirty patients underwent both tumor resection and radioactive seeds implanting. The patients were followed up for 1041 months.
RESULTS
All three patients receiving implanted radioactive seeds alone achieved CR Twenty-four patients treated by operation and radioactive seeds implanting had no local recurrence. The overall local control rate was 88%. The facial nerves were preserved in thirteen of fifteen patients without facial nerve palsy before treatment, and the facial nerve functioned well after operation. Four patients showed slight radiotherapeutic side effect.
CONCLUSIONS
Radioactive seeds implanting combined with operation or implanting radioactive seeds alone for the treatment of recurrent malignant parotid gland tumors could get good local control and treatment effects.
目的
探讨放射性粒子治疗复发性腮腺恶性肿瘤的疗效。
方法
回顾性分析33例接受放射性粒子治疗的复发性腮腺恶性肿瘤患者。3例患者单纯接受放射性粒子植入。30例患者接受了肿瘤切除及放射性粒子植入。对患者进行了1041个月的随访。
结果
3例单纯接受放射性粒子植入的患者均达到完全缓解。24例接受手术及放射性粒子植入治疗的患者无局部复发。总体局部控制率为88%。15例治疗前无面神经麻痹的患者中有13例面神经得以保留，术后面神经功能良好。4例患者出现轻微放疗副作用。
结论
放射性粒子植入联合手术或单纯放射性粒子植入治疗复发性腮腺恶性肿瘤可获得良好的局部控制和治疗效果。
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