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自体骨髓多能间充质基质细胞可刺激新血管生成,恢复微循环,并促进胃部慢性溃疡的愈合。

Multipotent mesenchymal stromal cells of autologous bone marrow stimulate neoangiogenesis, restore microcirculation, and promote healing of indolent ulcers of the stomach.

作者信息

Askarov M B, Onischenko N A

机构信息

Institute of Transplantology and Artificial Organs, Moscow.

出版信息

Bull Exp Biol Med. 2008 Oct;146(4):512-6. doi: 10.1007/s10517-009-0324-6.

Abstract

The effects of precultured multipotent mesenchymal stromal cells from autologous bone marrow on microcirculation and regeneration of experimental indolent stomach ulcer were studied in experiments on rats. It was demonstrated that precultured multipotent mesenchymal stromal bone marrow cells delivered to the zone of chronic gastric ulcer stimulate neoangiogemesis, improve microcirculation in the gastric mucosa, and promote ulcer healing.

摘要

在大鼠实验中研究了来自自体骨髓的预培养多能间充质基质细胞对实验性慢性胃溃疡微循环和再生的影响。结果表明,将预培养的多能间充质基质骨髓细胞输送到慢性胃溃疡区域可刺激新血管生成,改善胃黏膜微循环,并促进溃疡愈合。

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