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用于人骨髓间充质干细胞稳定转导的病毒载体:基于腺相关病毒和慢病毒的系统

Viral vectors for stable transduction of human mesenchymal stem cells: systems based on adeno-associated viruses and lentiviruses.

作者信息

Shakhbazau A V, Sevyaryn I N, Goncharova N V, Grinev V V, Kosmacheva S M, Potapnev M P

机构信息

Institute of Genetics and Cytology, National Academy of Sciences of Belarus, Minsk, Belarussia.

出版信息

Bull Exp Biol Med. 2008 Oct;146(4):531-3. doi: 10.1007/s10517-009-0320-x.

DOI:10.1007/s10517-009-0320-x
PMID:19489335
Abstract

We compared the efficiency of transduction with lentivectors based on HIV-1 and adeno-associated viruses serotype 2 and stability of transgene expression in human mesenchymal bone marrow stem cells.

摘要

我们比较了基于HIV-1的慢病毒载体和2型腺相关病毒转导人间充质骨髓干细胞的效率以及转基因表达的稳定性。

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Projection Stereolithographic Fabrication of BMP-2 Gene-activated Matrix for Bone Tissue Engineering.
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