Obermaier G, Geyer C, Hafner A, Schmidt P
Institut für Tierpathologie, Tiermedizinischen Fakultät der Ludwig-Maximilians-Universität München.
Tierarztl Prax. 1991 Aug;19(4):403-7.
A metastasizing glioma in a 4-year-old boxer bitch is described. Clinical symptoms included ataxia, blindness, and increased cervical pain sensation. The tumor metastasized to an extraordinary extent via the cerebrospinal fluid. Tumor masses surrounded the whole spinal cord including the cauda equina. Histological examination revealed a variable morphology of the glioma. Immunohistochemical investigations showed some tumor cells reacting with antibodies specific to GFAP and S-100 protein. In contrast, NSE, 200 kd NF, vimentin, and desmin could not be demonstrated within tumor cells. The results are discussed in detail.
