Ferrara M, Capozzi L, Russo R
Department of Pediatrics, The 2nd University of Naples, Naples, Italy.
Hematology. 2009 Jun;14(3):173-6. doi: 10.1179/102453309X402287.
In 102 children of both genders aged between 10 and 12 years affected by iron deficiency anaemia (IDA) from various causes, a retrospective study from 1999 to 2007 has been performed to investigate possible relationships between IDA and physical growth. Patients were divided into two groups according to gender. Hb, MCV, ferritin levels, HSDS and body mass index (BMI) were recorded to confirm the diagnosis and the height standard deviation scores were also evaluated. The causes of IDA were investigated. At study entry, both groups of patients, regardless of IDA etiology, had microcytic hypochromic anaemia with low ferritin level. Anthropometric parameters were also reduced. Significant differences of anthropometric parameters were found in both groups in relationship to various causes of IDA (p<0.05) (ANOVA). We conclude that IDA may influence physical growth and etiological factors play an important role on growth delay.
对102名年龄在10至12岁之间、因各种原因患有缺铁性贫血（IDA）的儿童（男女均有）进行了一项回顾性研究，该研究时间跨度为1999年至2007年，旨在调查IDA与身体生长之间可能存在的关系。根据性别将患者分为两组。记录血红蛋白（Hb）、平均红细胞体积（MCV）、铁蛋白水平、身高标准差分值（HSDS）和体重指数（BMI）以确诊病情，同时还评估了身高标准差分数。对IDA的病因进行了调查。在研究开始时，两组患者无论IDA病因如何，均患有小细胞低色素性贫血且铁蛋白水平较低。人体测量参数也有所降低。两组患者在与IDA的各种病因相关的人体测量参数方面存在显著差异（p<0.05）（方差分析）。我们得出结论，IDA可能会影响身体生长，病因因素对生长发育迟缓起着重要作用。
