Mukhtar M Shahid, Nishimura Marc T, Dangl Jeff
Department of Biology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.
Cell. 2009 May 29;137(5):804-6. doi: 10.1016/j.cell.2009.05.010.
NPR1 is a key transcriptional coregulator in plant defense responses. In this issue, Spoel et al. (2009) demonstrate that proteasome-mediated degradation of NPR1 in the nucleus promotes efficient expression of defense response genes following infection and prevents spurious activation of defensive responses in the absence of infection.
NPR1是植物防御反应中的关键转录共调节因子。在本期中,斯波尔等人(2009年)证明,蛋白酶体介导的细胞核内NPR1降解促进感染后防御反应基因的有效表达,并防止在未感染时防御反应的错误激活。