Acebes X, Arruga J, Acebes J J, Majos C, Muñoz S, Valero Isaac Alarcon
Ophthalmology Department, Bellvitge Hospital, L'Hospitalet de Llobregat, Spain.
J Neuroophthalmol. 2009 Jun;29(2):140-2. doi: 10.1097/WNO.0b013e3181a63583.
The original description of the Foster Kennedy syndrome included the clinical triad of optic disc pallor in one eye, optic disc edema in the other eye, and reduced olfaction caused by space-occupying anterior fossa masses. The optic disc pallor was attributed to direct compression of the intracranial optic nerve, the optic disc edema to increased intracranial pressure from mass effect, and the reduced olfaction to direct compression of the olfactory nerve. We report a patient with the ophthalmic features of the Foster Kennedy syndrome from meningiomatosis. A meningioma compressed one optic nerve to cause impaired visual function. Convexity meningiomas compressed the superior sagittal sinus to impair cerebral venous drainage, increased intracranial pressure, and papilledema in the other eye. This is the first report of the Foster Kennedy syndrome caused by this mechanism.
福斯特·肯尼迪综合征最初的描述包括临床三联征:一只眼视盘苍白,另一只眼视盘水肿,以及由前颅窝占位性肿块导致的嗅觉减退。视盘苍白归因于颅内视神经直接受压,视盘水肿归因于肿块效应引起的颅内压升高,嗅觉减退归因于嗅神经直接受压。我们报告一例因脑膜瘤病出现福斯特·肯尼迪综合征眼部特征的患者。一个脑膜瘤压迫一条视神经导致视觉功能受损。凸面脑膜瘤压迫上矢状窦,损害脑静脉引流,使颅内压升高,并导致另一只眼出现视乳头水肿。这是关于由该机制引起的福斯特·肯尼迪综合征的首例报告。