Limaye S R, Adler J
Ophthalmology Service, D.C. General Hospital, Washington 20003.
J Clin Neuroophthalmol. 1990 Sep;10(3):188-92.
A 49-year-old woman with a 6-year history of headaches was found to have a pale right optic disc with narrowed retinal arterioles and a congested left optic disc. Her visual acuity was 20/20 in each eye with normal visual fields in May 1983. These findings were attributed to a previous attack of non-arteritic anterior ischemic optic neuropathy (AION). She had a normal neurologic examination and a normal head computed tomographic (CT) scan performed 2 years prior to her initial ophthalmologic evaluation. She was followed over the next 2 years without change in her fundus examination. In December 1987, after a generalized tonic-clonic seizure, she was found to have a large right frontoparietal mass without direct impingement on the optic nerves, or chiasm on neuroradiological studies. At this time she developed marked papilledema in the left eye with a pale optic disc in the right eye remaining unchanged. Histopathological diagnosis of malignant glioma was made. Two diseases, ischemic optic neuropathy and glioma, in one patient represents a bizarre example of the pseudo-Foster Kennedy syndrome.
一名有6年头痛病史的49岁女性，被发现右侧视盘苍白，视网膜动脉变窄，左侧视盘充血。1983年5月，她双眼视力均为20/20，视野正常。这些表现归因于既往一次非动脉炎性前部缺血性视神经病变（AION）发作。在初次眼科评估前2年，她的神经系统检查正常，头部计算机断层扫描（CT）也正常。在接下来的2年里对她进行随访，眼底检查无变化。1987年12月，在一次全身强直阵挛发作后，经神经放射学检查发现她右侧额顶叶有一个大肿块，未直接压迫视神经或视交叉。此时，她左眼出现明显视乳头水肿，右眼苍白视盘无变化。病理组织学诊断为恶性胶质瘤。一名患者身上出现缺血性视神经病变和胶质瘤这两种疾病，是假性福斯特·肯尼迪综合征的一个奇特例子。
