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院前治疗对严重钝挫伤性脑损伤患者结局的影响:一项单中心研究。

Influence of prehospital treatment on the outcome of patients with severe blunt traumatic brain injury: a single-centre study.

机构信息

Department of Anaesthesia and Intensive Care, University of Trieste, Trieste, Italy.

出版信息

Eur J Emerg Med. 2009 Dec;16(6):312-7. doi: 10.1097/MEJ.0b013e32832d3aa1.

Abstract

UNLABELLED

AIM, PATIENTS, AND METHODS: To compare retrospectively the outcomes of patients with severe traumatic brain injury (Injury Severity Score, ISS total >or=15; the Abbreviated ISS-head, aISS(head) >or=9) admitted to our Intensive Care Unit by helicopter (helicopter emergency medical service, HEMS group = 89) with those transported by ambulance (GROUND group = 105) from January 2002 to December 2007.

RESULTS

The groups were comparable for age, Glasgow Coma Scale, ISS total, and aISS(head). The preadmission time of the HEMS group was significantly longer as compared with the GROUND group, but the interval from admission to definitive care was significantly shorter. In the prehospital phase, HEMS patients were more aggressively treated, as indicated by a significantly greater number of procedures performed (i.e. tracheal intubation and positioning of intravenous lines) and larger volumes of fluids infused. The overall mortality was lower in the HEMS than in the GROUND patients (21 vs. 25% respectively, P<0.05). The survival with or without only minor neurological disabilities was higher in the HEMS than in the GROUND group (54 vs. 44% respectively, P<0.05); among the survivors, the rate of severe neurological disabilities was lower in the HEMS than in the GROUND group (25 vs. 31%, P<0.05).

CONCLUSION

In our experience, aggressive early treatment of patients with severe traumatic brain injury was associated with a better outcome likely because of the prevention of secondary brain injury and a shorter interval elapsing from the trauma to definitive care despite more time spent on the scene by the intervening team.

摘要

目的

比较直升机转运(直升机紧急医疗服务组,HEMS 组=89 例)和救护车转运(地面转运组,GROUND 组=105 例)的严重创伤性脑损伤(ISS 总分为>或=15;简化 ISS-头部,aISS(头部)>或=9)患者的结局。

患者和方法

回顾性比较 2002 年 1 月至 2007 年 12 月入住我院重症监护病房的患者。

结果

两组患者的年龄、Glasgow 昏迷评分、ISS 总评分和 aISS(头部)评分相似。HEMS 组患者的入院前时间明显长于 GROUND 组,但从入院到确定性治疗的间隔时间明显缩短。在院前阶段,HEMS 患者的治疗更积极,表现为进行的操作(如气管插管和静脉置管)和输注的液体量明显更大。HEMS 组患者的总死亡率低于 GROUND 组(分别为 21%和 25%,P<0.05)。HEMS 组患者的生存且仅有轻微神经功能障碍的比例高于 GROUND 组(分别为 54%和 44%,P<0.05);在幸存者中,HEMS 组患者的严重神经功能障碍比例低于 GROUND 组(分别为 25%和 31%,P<0.05)。

结论

根据我们的经验,对严重创伤性脑损伤患者进行积极的早期治疗与较好的结局相关,可能是因为防止了继发性脑损伤,并且从创伤到确定性治疗的时间间隔缩短,尽管介入团队在现场花费的时间更多。

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