Guldager H, Sørensen M B, Hjortsø N C
Kommunehospitalet, Laegeambulancen i København.
Ugeskr Laeger. 1991 Sep 9;153(37):2544-6.
In a prospective investigation lasting for one year, the medically staffed ambulance in Copenhagen registered patients under the age of 60 years with asthma who developed respiratory arrest outside hospital. The circumstances involved in the acute serious cases were illustrated as far as possible by review of the case records and interviews with the surviving patients. Five patients participated in the investigation. All of these were young with a median age of 24 years (19-28). Two patients had cardiac arrest, four patients survived after tracheal intubation at the site of the onset of illness and subsequent mechanical ventilation. One patient died in hospital on account of anoxic encephalopathy. The common denominators of all of the patients were that the condition had been recognized for many years, that before the attack involved they had been well and without asthmatic symptoms, the attack commenced hyper-acutely and the patients had not taken medicine regularly during a prolonged period. On the basis of these observations, the present authors recommend that young patients with asthma should receive optimal medication and that the necessity of taking the prescribed medicine despite possible good health should be emphasized.
在一项为期一年的前瞻性调查中,哥本哈根配备医务人员的救护车记录了60岁以下院外发生呼吸骤停的哮喘患者。通过查阅病例记录和对幸存患者进行访谈,尽可能详细地说明了这些急性重症病例的相关情况。五名患者参与了此次调查。他们均为年轻人,中位年龄24岁(19 - 28岁)。两名患者发生心脏骤停,四名患者在发病现场气管插管并随后接受机械通气后存活。一名患者因缺氧性脑病死于医院。所有患者的共同特点是病情已被确诊多年,在发作前身体状况良好且无哮喘症状,发作起病极快,并且患者在很长一段时间内未规律服药。基于这些观察结果,本文作者建议哮喘青年患者应接受最佳药物治疗,并强调即便可能身体状况良好也需按医嘱服药的必要性。