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[急性肾功能不全的连续性动静脉血液透析。对23例患者在2年期间治疗的疗效回顾]

[Continuous arteriovenous hemodialysis in acute renal insufficiency. Review of therapeutical results among 23 patients treated over a period of 2 years].

作者信息

Bredahl C, Nielsen G, Larsen U T

机构信息

Medicinsk afdeling C, Aalborg Sygehus.

出版信息

Ugeskr Laeger. 1991 Sep 16;153(38):2628-31.

PMID:1949271
Abstract

In critically ill patients with acute renal failure and unstable circulation, dialysis employing conventional haemodialysis may prove technically difficult. If, however, continuous arterio-venous haemofiltration is employed, the haemodynamic problems may be overwon but the method does not always provide effective control of azotaemia. Continuous arterio-venous haemodialysis (KAVHD) is a combination of ultrafiltration and dialysis. The efficacy of KAVHD was investigated retrospectively in 23 critically ill patients with acute renal failure and unstable circulation. All of the patients achieved acceptable steady state concentrations for serum creatinine and carbamide. Four out of five patients with hyperkalaemia obtained normal serum potassium after the first 24 hours of treatment with KAVHD. The average filtration volume was 6.1 1/24 hours, sufficient to provide parenteral nutrition and intravenous infusion and to maintain the negative fluid balance simultaneously. Fifteen patients (65%) died during the intensive course of treatment but none died from complications of KAVHD or renal failure. Renal function was reestablished in eight patients and seven of these could be discharged alive. KAVHD is an effective and simple method of treating critically ill patients with acute renal failure and unstable circulation.

摘要

对于患有急性肾衰竭且循环不稳定的重症患者,采用传统血液透析进行透析在技术上可能存在困难。然而,如果采用连续性动静脉血液滤过,血流动力学问题或许能够克服,但该方法并不总能有效控制氮质血症。连续性动静脉血液透析(KAVHD)是超滤和透析的结合。对23例患有急性肾衰竭且循环不稳定的重症患者进行了回顾性研究,以探讨KAVHD的疗效。所有患者的血清肌酐和尿素均达到了可接受的稳态浓度。五例高钾血症患者中,有四例在接受KAVHD治疗的最初24小时后血清钾恢复正常。平均滤过量为6.1升/24小时,足以提供肠外营养和静脉输液,并同时维持负水平衡。15例患者(65%)在强化治疗过程中死亡,但无一例死于KAVHD或肾衰竭并发症。8例患者肾功能得以恢复,其中7例存活出院。KAVHD是治疗患有急性肾衰竭且循环不稳定的重症患者的一种有效且简便的方法。

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