Partington Susan N, Steber Dale L, Blair Kathleen A, Cisler Ron A
Department of Health Sciences, College of Health Sciences, University of Wisconsin, Milwaukee,WI, USA.
Perspect Sex Reprod Health. 2009 Jun;41(2):101-9. doi: 10.1363/4110109.
Teenagers are more likely than older women to have a low-birth-weight infant or a preterm birth, and the risks may be particularly high when they have a second birth. Identifying predictors of these outcomes in second teenage births is essential for developing preventive strategies.
Birth certificate data for 1993-2002 were linked to identify second births to Milwaukee teenagers. Predictors of having a low-birth-weight second infant or a preterm second birth were identified using logistic regression.
The same proportion of first and second infants were low-birth-weight (12%), but second births were more likely than first births to be preterm (15% vs. 12%). In analyses that adjusted for demographic, pregnancy and behavioral characteristics, the odds that a second infant was low-birth-weight or preterm were elevated if the mother smoked during pregnancy (odds ratios, 2.2 and 1.9, respectively), had inadequate prenatal weight gain (1.8 and 1.4), had an interpregnancy interval of less than 18 months (1.6-2.9 and 1.4-2.3) or was black (2.7 and 1.7). Women who had received an adequate level of prenatal care had reduced odds of both outcomes (0.6 and 0.4). Women younger than 16 also had increased odds of having a low-birth-weight second infant. Further adjustment for socioeconomic characteristics yielded largely the same results. In addition, women who were unmarried or did not identify a father were at increased risk of both outcomes (1.5 for each), and poor women were at risk of having a low-birth-weight infant (1.3).
Predictors of poor birth outcomes include modifiable behaviors. Prenatal interventions addressing these behaviors could help improve outcomes.
青少年比年长女性更有可能生出低体重婴儿或早产,而且她们第二次生育时这些风险可能特别高。识别青少年第二次生育这些结局的预测因素对于制定预防策略至关重要。
将1993 - 2002年的出生证明数据相链接,以识别密尔沃基青少年的第二次生育情况。使用逻辑回归确定第二次生育时生出低体重婴儿或早产的预测因素。
第一胎和第二胎低体重婴儿的比例相同(12%),但第二次生育比第一次生育更易早产(15%对12%)。在针对人口统计学、妊娠和行为特征进行调整的分析中,如果母亲在孕期吸烟(比值比分别为2.2和1.9)、孕期体重增加不足(1.8和1.4)、两次妊娠间隔小于18个月(1.6 - 2.9和1.4 - 2.3)或为黑人(2.7和1.7),则第二个婴儿为低体重或早产的几率会升高。接受了足够产前护理的女性出现这两种结局的几率降低(0.6和0.4)。年龄小于16岁的女性生出低体重第二个婴儿的几率也增加。对社会经济特征进行进一步调整后得出的结果大致相同。此外,未婚或未确定父亲身份的女性出现这两种结局的风险增加(每种情况的比值比均为1.5),贫困女性有生出低体重婴儿的风险(1.3)。
不良出生结局的预测因素包括可改变的行为。针对这些行为的产前干预措施有助于改善结局。