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[不同类型肾结石中的总尿蛋白]

[Total urinary protein in different types of nephrolithiasis].

作者信息

Bilobrov V M, Mironov O L, Minas'iants E Z, Bilobrova I G, Shul'gin N M

出版信息

Urol Nefrol (Mosk). 1991 Jul-Aug(4):33-7.

PMID:1949415
Abstract

In 26 healthy individuals and 114 patients with urolithiasis, total urine protein levels were measured in a single sample by using the stain ponceau S. The findings were statistically analyzed. The levels of the protein were found to be 27-80 mg/l in the healthy individuals, while the distribution of the data was asymmetric as viewed from high values. The patients with urolithiasis exhibited their protein levels according to the type of nephrolithiasis. Proteinuria was demonstrated to be less pronounced in patients with oxalate and urate nephrolithiasis than in patients with coral phosphate calculi. There was a substantial asymmetry in the distribution of total urine protein for all the examined groups of urolithiasis patients, as well as great dispersion values, which fails to regard the parameter alone as a diagnostic criterion for the type of nephrolithiasis. At the same time it was noted that simultaneous examination of the levels of total protein, uric acid, potassium, and sodium enabled the type of a concrement (oxalate or phosphate) to be in vivo estimated with approximately 85% probability.

摘要

在26名健康个体和114名尿石症患者中,使用丽春红S对单个样本中的总尿蛋白水平进行了测量。对结果进行了统计分析。发现健康个体中的蛋白水平为27 - 80毫克/升,而从高值来看数据分布不对称。尿石症患者根据肾结石的类型呈现出不同的蛋白水平。结果表明,草酸钙和尿酸肾结石患者的蛋白尿不如珊瑚磷酸钙结石患者明显。所有接受检查的尿石症患者组的总尿蛋白分布存在显著不对称,且离散值较大,这使得不能仅将该参数作为肾结石类型的诊断标准。同时还注意到,同时检测总蛋白、尿酸、钾和钠的水平能够以大约85%的概率在体内估计结石的类型(草酸钙或磷酸盐)。

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