Dumoulin G, Haton D, Wolf J P, Henriet M T, Nguyen N U, Mougin C, Saint-Hillier Y, Combes M, Berthelay S
Nephrologie. 1984;5(5):189-91.
The purpose of this study was to determine and to compare the frequency of hypercalciuria, hyperoxaluria and hyperuricosuria in 49 patients with a pure or mixed calcium oxalate urolithiasis. During this study, all patients were on a normal diet and had no special disease or medication. We noted that hypercalciuria (35%) and hyperoxaluria (24%) were more often associated (18%) than isolated (8 and 2%). They were more frequent in mixed stones (44% et 39%) than in pure one (29% and 16%). Hyperuricuria (39%) had a same frequency wathever the renal stone type may be. A same frequency was noted when hyperuricuria was associated with hypercalciuria and hyperoxaluria (12%) or isolated (14%). None of these three biologic disturbances was observed in 45% of our patients.
本研究的目的是确定并比较49例单纯或混合草酸钙尿路结石患者中高钙尿症、高草酸尿症和高尿酸尿症的发生率。在本研究期间,所有患者均采用正常饮食,且无特殊疾病或用药情况。我们注意到,高钙尿症(35%)和高草酸尿症(24%)同时出现的情况(18%)比单独出现的情况(8%和2%)更为常见。它们在混合结石患者中(44%和39%)比在单纯结石患者中(29%和16%)更为频繁。无论肾结石类型如何,高尿酸尿症(39%)的发生率相同。当高尿酸尿症与高钙尿症和高草酸尿症同时出现(12%)或单独出现(14%)时,发生率也相同。45%的患者未观察到这三种生物紊乱中的任何一种。