Stief C G, Thon W F, Djamilian M, de Riese W, Fritz K W, Allhoff E P, Jonas U
Department of Urology, University Clinic, Hannover, FRG.
Urol Res. 1991;19(5):277-80. doi: 10.1007/BF00299057.
Recording of cavernous electric activity was performed in 178 patients with erectile dysfunction and in 37 normal patients. In 34/37 normal patients, potentials of a uniform shape were recorded during flaccidity: At cut-off frequencies of 0.5-500 Hz, the length was 8-18 (mean 12.8, SD 2.8), the amplitude 250-750 (mean 444, SD 109) microV, and the polyphasity 8-22 (mean 13.8, SD 3.3). In impotent patients with upper motor neuron lesions or peripheral lesions, specific types of potentials were observed. In 11/14 impotent patients with insulin-dependent diabetes for over 20 years and clinical findings of cavernous myopathy, potentials showed low amplitude, irregular shape, and slow depolarizations. In 51% of the consecutive impotent patients, abnormal findings of cavernous electric activity were recorded. Our clinical study suggests that single potential analysis of cavernous electric activity (SPACE) may be useful in the diagnosis of cavernous autonomic neuropathy and cavernous smooth muscle myopathy.
对178例勃起功能障碍患者和37例正常患者进行了海绵体电活动记录。在37例正常患者中的34例，疲软状态下记录到形状一致的电位：在0.5 - 500Hz的截止频率下，长度为8 - 18（平均12.8，标准差2.8），幅度为250 - 750（平均444，标准差109）微伏，多相性为8 - 22（平均13.8，标准差3.3）。在上运动神经元病变或周围神经病变的阳痿患者中，观察到特定类型的电位。在14例胰岛素依赖型糖尿病超过20年且有海绵体肌病临床表现的阳痿患者中的11例，电位显示为低幅度、不规则形状和缓慢去极化。在连续的阳痿患者中，51%记录到海绵体电活动异常结果。我们的临床研究表明，海绵体电活动单电位分析（SPACE）可能有助于诊断海绵体自主神经病变和海绵体平滑肌肌病。
