Stief C G, Bähren W, Gall H, Scherb W
Department of Urology, Academic Hospital, Ulm, Germany.
J Urol. 1988 Apr;139(4):734-7. doi: 10.1016/s0022-5347(17)42613-9.
A multidisciplinary study was performed on 200 consecutive patients with erectile dysfunction more than 1 year in duration, which included a standardized intracavernous injection of a vasoactive substance mixture (15 mg. per ml. papaverine plus 0.5 mg. per ml. phentolamine). The multidisciplinary findings correlated well with the intracavernous dose needed for full erection. The group without pathological hemodynamic findings (36 patients) needed an average of 0.67 ml. and the group with pathological inflow (107) needed an average of 1.07 ml. In the venous insufficiency group (57 patients) only 18 achieved full erections with an average of 2.1 ml. (39 achieved tumescence only to 3 ml.). The results show that standardized intracavernous injection of a vasoactive substance mixture is a useful method to evaluate penile hemodynamics. This pharmacological test appears to be effective in the differential diagnosis of nonvascular and vascular erectile dysfunction.
对200例病程超过1年的勃起功能障碍患者进行了一项多学科研究，其中包括对血管活性物质混合物进行标准化海绵体内注射（每毫升15毫克罂粟碱加每毫升0.5毫克酚妥拉明）。多学科研究结果与完全勃起所需的海绵体内注射剂量密切相关。无病理性血流动力学结果的组（36例患者）平均需要0.67毫升，有病理流入的组（107例）平均需要1.07毫升。在静脉功能不全组（57例患者）中，只有18例实现了完全勃起，平均用量为2.1毫升（39例仅勃起至3毫升）。结果表明，血管活性物质混合物的标准化海绵体内注射是评估阴茎血流动力学的一种有用方法。这种药理学测试似乎对非血管性和血管性勃起功能障碍的鉴别诊断有效。
