两名儿童在使用治疗剂量的克拉霉素时可能出现了视幻觉。
Visual hallucinations possibly associated with clarithromycin administration at therapeutic dosage in two children.
作者信息
Erkek Nilgun, Senel Saliha, Karacan Candemir
机构信息
Department of Pediatrics, Dr. Sami Ulus Children's Hospital, Telsizler, Ankara, Turkey.
出版信息
Med Princ Pract. 2009;18(4):332-4. doi: 10.1159/000215734. Epub 2009 Jun 2.
OBJECTIVE
Our aim was to present 2 children with visual hallucinations possibly associated with clarithromycin administration at therapeutic dosage.
SUBJECTS AND METHODS
Two children were admitted to our hospital with sudden onset of visual hallucinations after taking clarithromycin at therapeutic dosage by mouth. Physical examination, laboratory investigations and imaging studies were normal. The symptoms gradually disappeared once the clarithromycin therapy had been discontinued, making us suspect clarithromycin as the agent responsible for the visual hallucinations. They were observed monthly for a year without any symptoms or further treatment.
CONCLUSION
This report highlights hallucinations due to therapeutic doses of clarithromycin therapy as a possible new side effect in children.
目的
我们的目的是报告2例可能与服用治疗剂量克拉霉素有关的视幻觉患儿。
对象与方法
2例患儿口服治疗剂量的克拉霉素后突然出现视幻觉而入住我院。体格检查、实验室检查及影像学检查均正常。停用克拉霉素治疗后症状逐渐消失，这使我们怀疑克拉霉素是导致视幻觉的药物。对他们进行了为期一年的每月观察，未出现任何症状，也未进行进一步治疗。
结论
本报告强调治疗剂量克拉霉素治疗导致的幻觉可能是儿童一种新的副作用。
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