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残余肾功能及腹膜透析在无尿患者中的重要性。

Importance of residual renal function and peritoneal dialysis in anuric patients.

作者信息

Carvalho Maria João, Rodrigues Anabela

出版信息

Contrib Nephrol. 2009;163:155-160. doi: 10.1159/000223794. Epub 2009 Jun 3.

DOI:10.1159/000223794
PMID:19494609
Abstract

Residual renal function (RRF) impacts on patient survival and quality of life of dialysis patients. Its longer preservation is a major advantage of peritoneal dialysis (PD) and should be also a target of adequacy, beyond Kt/V. Anuric patients no longer benefit from such PD advantage, depending only on dialysis schedule to achieve adequate small solute and volume control. This challenge can be successfully dealt with by using automated PD, icodextrine, low-glucose degradation products and individualized PD profiles. There is evidence that PD advances allow nowadays satisfactory patient survival while keeping the benefits of home dialysis and preserving vascular network. An integrated care plan should consider both medical indications and patient preference aiming for the longer total patient survival, even if transfer to HD might be later needed as part of individualized renal replacement strategy.

摘要

残余肾功能(RRF)对透析患者的生存和生活质量有影响。其更长时间的保留是腹膜透析(PD)的一个主要优势,并且应该也是除Kt/V之外充分性的一个目标。无尿患者不再从这种PD优势中获益,仅依赖透析方案来实现充分的小分子溶质清除和容量控制。通过使用自动化腹膜透析、艾考糊精、低葡萄糖降解产物和个体化腹膜透析方案,这一挑战能够得到成功应对。有证据表明,如今腹膜透析的进展在保持家庭透析的益处和保留血管网络的同时,能使患者获得令人满意的生存。一个综合护理计划应同时考虑医学指征和患者偏好,目标是实现患者更长的总体生存,即便作为个体化肾脏替代策略的一部分,后期可能需要转为血液透析。

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