Longbottom C, Ekstrand K, Zero D
Monogr Oral Sci. 2009;21:149-155. doi: 10.1159/000224219. Epub 2009 Jun 3.
Preventive treatment options can be divided into primary, secondary and tertiary prevention techniques, which can involve patient- or professionally applied methods. These include: oral hygiene (instruction), pit and fissure sealants ('temporary' or 'permanent'), fluoride applications (patient- or professionally applied), dietary assessment and advice (modification), other measures to help remineralize demineralized tissue and other measures to help modify the biofilm to reduce the cariogenic challenge. There is a considerable body of strong evidence supporting the use of specific techniques for primary prevention of caries in children, e.g. pit and fissure sealants and topically applied fluorides (including patient-applied fluoride toothpastes and professionally applied fluoride varnishes), but limited strong evidence for these techniques for secondary prevention--i.e. where early to established lesions with ICDAS codes 1-4 (and also the severer lesions coded 5 or 6) are involved--and in relation to adults. This lack of evidence reflects a shortage of high-quality trials in the area, as opposed to a series of good studies showing no effect. Since there is also limited longitudinal evidence supporting conventional operative care, and since controlling the caries process prior to first restoration is the key to breaking the repair cycle and improving care for patients, future research should address the shortcomings in the current level of supporting evidence for the various traditional preventive treatment options.
预防性治疗方法可分为一级、二级和三级预防技术,这些技术可涉及患者自行应用或专业人员应用的方法。这些方法包括:口腔卫生(指导)、窝沟封闭剂(“临时”或“永久”)、氟化物应用(患者自行应用或专业人员应用)、饮食评估与建议(调整)、其他有助于使脱矿组织再矿化的措施以及其他有助于改变生物膜以降低致龋风险的措施。有大量有力证据支持在儿童龋齿一级预防中使用特定技术,例如窝沟封闭剂和局部应用氟化物(包括患者自行应用的含氟牙膏和专业人员应用的氟化物 varnishes),但对于这些技术在二级预防中的应用——即涉及国际龋病检测与评估系统(ICDAS)编码为 1 - 4 的早期至已确诊病变(以及编码为 5 或 6 的更严重病变)——以及在成人中的应用,有力证据有限。这种证据不足反映了该领域高质量试验的缺乏,而不是一系列良好研究表明这些技术无效。由于支持传统手术治疗的纵向证据也有限,并且由于在首次修复前控制龋病进程是打破修复循环并改善患者护理的关键,未来的研究应解决当前各种传统预防性治疗方法支持证据水平的不足之处。