Zaveri Gautam R, Mehta Satyen S
Jaslok Hospital and Research Centre, Wockhardt Hospital and Research Centre, Mumbai, Maharashtra, India.
J Spinal Disord Tech. 2009 Jun;22(4):257-62. doi: 10.1097/BSD.0b013e31818859d0.
Retrospective case study.
We present a retrospective clinical study of 15 patients with lumbar and lumbosacral tuberculosis treated by transforaminal lumbar interbody fusion and posterior instrumentation. The purpose is to determine the clinical efficacy of such surgical treatment for lumbar tuberculosis.
The goals of management of tuberculous spondylodiscitis are to eradicate infection and to prevent or treat deformity, instability, and neurologic deficit. Various methods of surgical debridement and fusion have been described for the lumbar spine. However, there have been few reports on the treatment of patients with peridiscal type of lumbar tuberculosis by transforaminal debridement and interbody fusion along with posterior stabilization using pedicle screw fixation.
Our study comprises 9 males and 6 females with an average age of 47 years treated with the above given surgical procedure. All patients had single motion segment involvement. The average follow-up is 41 months. We have evaluated the following parameters: healing of disease, deformity correction and its maintenance, improvement in neurology, fusion of affected segment, and functional outcome.
The mean preoperative local lordotic angle of -3.7 degrees was corrected surgically to a mean of 5 degrees immediately postoperatively. The mean local lordosis at final follow-up (mean 41 mo, 26 to 69 mo) was 4 degrees. Using the modified radiologic criteria of Lee et al, we found that 13 patients had definitive fusion and 2 patients had probable fusion. All patients had healing of disease and there was no recurrence at final follow-up. Using the criteria of Kirkaldy-Willis et al, the functional outcome was found to be excellent in 8, good in 5, and fair in 2 patients.
Transforaminal lumbar interbody fusion with pedicle screw fixation is a simple, safe, and effective procedure for treatment of selected patients suffering from lumbar and lumbosacral tuberculosis.
回顾性病例研究。
我们对15例采用经椎间孔腰椎椎体间融合术及后路内固定治疗的腰椎和腰骶部结核患者进行了一项回顾性临床研究。目的是确定这种手术治疗腰椎结核的临床疗效。
结核性脊椎椎间盘炎的治疗目标是根除感染并预防或治疗畸形、不稳定和神经功能缺损。对于腰椎,已经描述了各种手术清创和融合方法。然而,关于经椎间孔清创、椎体间融合并结合椎弓根螺钉固定进行后路稳定治疗椎间盘周围型腰椎结核患者的报道很少。
我们的研究包括9例男性和6例女性,平均年龄47岁,接受了上述手术治疗。所有患者均为单一运动节段受累。平均随访时间为41个月。我们评估了以下参数:疾病愈合情况、畸形矫正及其维持情况、神经功能改善情况、受累节段融合情况以及功能结果。
术前平均局部前凸角为-3.7度,术后立即通过手术矫正至平均5度。末次随访时(平均41个月,26至69个月)的平均局部前凸为4度。使用Lee等人修改后的影像学标准,我们发现13例患者有明确融合,2例患者可能融合。所有患者疾病均愈合,末次随访时无复发。根据Kirkaldy-Willis等人的标准,发现8例患者功能结果优秀,5例良好,2例一般。
经椎间孔腰椎椎体间融合术结合椎弓根螺钉固定是治疗选定的腰椎和腰骶部结核患者的一种简单、安全且有效的方法。