Palumbo A, Sezer O, Kyle R, Miguel J S, Orlowski R Z, Moreau P, Niesvizky R, Morgan G, Comenzo R, Sonneveld P, Kumar S, Hajek R, Giralt S, Bringhen S, Anderson K C, Richardson P G, Cavo M, Davies F, Bladé J, Einsele H, Dimopoulos M A, Spencer A, Dispenzieri A, Reiman T, Shimizu K, Lee J H, Attal M, Boccadoro M, Mateos M, Chen W, Ludwig H, Joshua D, Chim J, Hungria V, Turesson I, Durie B G M, Lonial S
Divisione di Ematologia dell'Università di Torino, Azienda Ospedaliera S. Giovanni Battista, Ospedale Molinette, Torino 10126, Italy.
Leukemia. 2009 Oct;23(10):1716-30. doi: 10.1038/leu.2009.122. Epub 2009 Jun 4.
In 2005, the first guidelines were published on the management of patients with multiple myeloma (MM). An expert panel reviewed the currently available literature as the basis for a set of revised and updated consensus guidelines for the diagnosis and management of patients with MM who are not eligible for autologous stem cell transplantation. Here we present recommendations on the diagnosis, treatment of newly diagnosed non-transplant-eligible patients and the management of complications occurring during induction therapy among these patients. These guidelines will aid the physician in daily clinical practice and will ensure optimal care for patients with MM.
2005年，多发性骨髓瘤（MM）患者管理的首个指南发布。一个专家小组对现有文献进行了审查，以此为基础制定了一套修订和更新的共识指南，用于指导不符合自体干细胞移植条件的MM患者的诊断和管理。在此，我们提出关于新诊断的不符合移植条件患者的诊断、治疗以及这些患者诱导治疗期间并发症管理的建议。这些指南将有助于医生在日常临床实践中为MM患者提供最佳治疗。
