Catalá López Ferrán, Alvarez Martín Elena, Gènova Maleras Ricard, Morant Ginestar Consuelo
Instituto de Salud Carlos III, Ministerio de Ciencia e Innovación, C/ Sinesio Delgado 6, Pabellón 13. 28029 Madrid.
Rev Esp Salud Publica. 2009 Jan-Feb;83(1):137-51. doi: 10.1590/s1135-57272009000100011.
The Carlos III Health Institute (Instituto de Salud Carlos III - Spain) allocates funding to health research support in the Spanish National Health System (NHS). This study aimed to analyse the correlation of health research fund allocations in the NHS and the burden of disease in Spanish population.
Cross-sectional study. Burden of disease measures were calculated: disability-adjusted life-years (DALYs), years of life lost (YLLs) and mortality by cause. A correlation analysis (Spearman s Rho) was applied to test the association between these measures and 2006/2007 health research funding.
Using disease categories (n=21), the correlation between funding and disease-burden measures is: DALY (r=0.72; p <0.001), mortality (r=0.60; p=0.004) and YLL (r=0.56; p=0.008). By disease-specific subcategories (n=52): DALY (r=0.55; p<0.001), mortality (r=0.54; p <0.001) and YLL (r=0.55; p <0.001). Malignant neoplasms, neuropsychiatric conditions, cardiovascular diseases and infectious and parasitic diseases receive the greater health research funding support. However, the higher funds allocated per DALY lost ratios were for blood and endocrine disorders, infectious and parasitic diseases and congenital anomalies.
Our analysis suggests that NHS research funding is positive moderately high-associated with the burden of disease in Spain, although there exists certain diseases categories that are over or under-funded in relation to their burden generated. In health planning, burden of disease studies contributes with useful information for setting health research priorities.
卡洛斯三世卫生研究所(西班牙)为西班牙国家卫生系统的卫生研究支持分配资金。本研究旨在分析国家卫生系统中卫生研究资金分配与西班牙人群疾病负担之间的相关性。
横断面研究。计算疾病负担指标:伤残调整生命年(DALYs)、寿命损失年数(YLLs)和死因死亡率。应用相关性分析(Spearman秩相关系数)来检验这些指标与2006/2007年卫生研究资金之间的关联。
按疾病类别(n = 21),资金与疾病负担指标之间的相关性为:伤残调整生命年(r = 0.72;p < 0.001)、死亡率(r = 0.60;p = 0.004)和寿命损失年数(r = 0.56;p = 0.008)。按特定疾病亚类(n = 52):伤残调整生命年(r = 0.55;p < 0.001)、死亡率(r = 0.54;p < 0.001)和寿命损失年数(r = 0.55;p < 0.001)。恶性肿瘤、神经精神疾病、心血管疾病以及传染病和寄生虫病获得了更多的卫生研究资金支持。然而,每伤残调整生命年损失所分配的资金比例较高的是血液和内分泌疾病、传染病和寄生虫病以及先天性异常。
我们的分析表明,国家卫生系统的研究资金与西班牙的疾病负担呈中等偏高的正相关,尽管存在某些疾病类别,其资金投入与其产生的负担相比过多或过少。在卫生规划中,疾病负担研究为确定卫生研究重点提供了有用信息。