Zhang Hongjun, Li John K-J
Biomedical Engineering, Rutgers University, 599 Taylor Road, BME, Piscataway, NJ 08854, USA.
Cardiovasc Eng. 2009 Jun;9(2):39-48. doi: 10.1007/s10558-009-9074-3. Epub 2009 Jun 3.
A frequency domain distributed 55 segment arterial model was constructed from the reflection perspective to predict pressure waveforms in the large systemic arteries. At any node, the predicted pressure waveform was the combination of a forward propagating waveform and a number of repeatedly reflected waveforms from any possible sites. This approach ensured that any single reflected waveform could be traced back to its origin, and thus the causal-effect relation would be precisely known. This model was evaluated in terms of branch reflection coefficient, terminal vascular bed behavior, and wall viscoelasticity. It was found that the model predicted pressure waveforms were most sensitive to the branch reflection coefficient, and this led to the adoption of the zero-forward reflection assumption at branches. The model-predicted pressure waveforms compared favorably with realistic blood pressure waveforms, especially in the upper limbs. For lower limbs, finer segmentation could further improve the predictions.
从反射角度构建了一个频域分布式55段动脉模型，以预测大的体循环动脉中的压力波形。在任何节点处，预测的压力波形是向前传播的波形与来自任何可能部位的多个反复反射波形的组合。这种方法确保了任何单个反射波形都可以追溯到其源头，从而可以精确地知道因果关系。该模型从分支反射系数、末端血管床行为和壁粘弹性方面进行了评估。结果发现，该模型预测的压力波形对分支反射系数最为敏感，这导致在分支处采用零向前反射假设。该模型预测的压力波形与实际血压波形相比具有优势，尤其是在上肢。对于下肢，更精细的分段可以进一步改善预测。
