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输血后发生致命性小肠结肠炎耶尔森菌(血清型0:5,27)败血症。

Fatal Yersinia enterocolitica (serotype 0:5,27) sepsis after blood transfusion.

作者信息

Stubbs J R, Reddy R L, Elg S A, Perry E H, Adcock L L, McCullough J

机构信息

Department of Laboratory Medicine and Pathology, University of Minnesota Medical School, Minneapolis.

出版信息

Vox Sang. 1991;61(1):18-23. doi: 10.1111/j.1423-0410.1991.tb00921.x.

DOI:10.1111/j.1423-0410.1991.tb00921.x
PMID:1949705
Abstract

Septicemia is a rare complication of blood transfusion. This is probably primarily due to the use of sealed disposable containers for blood collection and the storage of red cell-containing components at 4 degrees C. However, despite these measures, septicemia due to blood transfusion continues to occur. We report here a fatal case of Yersinia enterocolitica septicemia due to a contaminated unit of red cells which was collected from an apparently healthy, asymptomatic blood donor. The organism grows at cold temperature and multiplies during storage of red blood cell-containing components. Contaminated components do not show any visible abnormalities. The possibility of transfusion-transmitted Y. enterocolitica should be considered in patients who have symptoms of sepsis or shock following transfusion.

摘要

败血症是输血的一种罕见并发症。这可能主要归因于使用密封的一次性采血容器以及将含红细胞成分储存在4摄氏度的环境中。然而,尽管采取了这些措施,输血导致的败血症仍不断发生。我们在此报告一例因受污染的红细胞单位导致的小肠结肠炎耶尔森菌败血症致死病例,该单位红细胞采自一名表面健康、无症状的献血者。该病菌在低温下生长,并在含红细胞成分储存期间繁殖。受污染的成分没有任何可见异常。对于输血后出现败血症或休克症状的患者,应考虑输血传播小肠结肠炎耶尔森菌的可能性。

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引用本文的文献

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Red blood cell storage lesion: causes and potential clinical consequences.红细胞储存损伤:原因及潜在临床后果。
Blood Transfus. 2019 Jan;17(1):27-52. doi: 10.2450/2019.0217-18.
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Yersinia enterocolitica: the charisma continues.小肠结肠炎耶尔森菌:魅力依旧。
Clin Microbiol Rev. 1997 Apr;10(2):257-76. doi: 10.1128/CMR.10.2.257.
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Yersinia enterocolitica septicaemia from transfusion of red cell concentrate stored for 16 days.因输注储存16天的浓缩红细胞导致小肠结肠炎耶尔森菌败血症。
J Clin Pathol. 1993 May;46(5):477-8. doi: 10.1136/jcp.46.5.477.
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Transfusion-associated bacterial sepsis.输血相关细菌性败血症
Clin Microbiol Rev. 1994 Jul;7(3):290-302. doi: 10.1128/CMR.7.3.290.