University of Central Lancashire, Preston, UK.
Int Psychogeriatr. 2009 Dec;21(6):1190-5. doi: 10.1017/S1041610209990378. Epub 2009 Jun 5.
The elderly are at high risk of developing tuberculosis. The prevalence and incidence of depression and anxiety are higher in those with tuberculosis than in the general population. A positive correlation between national suicide rates and rates of mortality due to tuberculosis has been reported.
The relationships between elderly suicide rates and (i) the prevalence of tuberculosis, (ii) the proportion of detected cases of tuberculosis, and (iii) the proportion of cured cases of tuberculosis were examined in a cross-national study using data from the World Health Organization and the United Nations.
There were no significant correlations between elderly suicide rates and the prevalence of tuberculosis and the proportion of detected cases of tuberculosis. There were weak but significant negative correlations between the proportion of cured cases of tuberculosis and suicide rates for both sexes in both elderly age-bands.
Caution should be exercised in interpreting the findings and the direction of the causal relationship from this cross-sectional ecological study because of ecological fallacy. However, if the findings are true then potentially the study has important implications for prevention of elderly suicides, particularly in countries with a high prevalence of tuberculosis.
老年人患结核病的风险较高。与一般人群相比,结核病患者中抑郁和焦虑的患病率和发病率更高。据报道,国家自杀率与结核病死亡率之间呈正相关。
本跨国研究使用世界卫生组织和联合国的数据,考察了老年人自杀率与以下因素之间的关系:(i)结核病的流行率,(ii)结核病检出病例的比例,以及(iii)结核病治愈病例的比例。
老年人自杀率与结核病的流行率和结核病检出病例的比例之间无显著相关性。在两个老年年龄组中,结核病治愈病例的比例与两性自杀率之间存在微弱但显著的负相关。
由于存在生态学谬误,因此在解释这些发现和从这项横断面生态学研究中得出因果关系的方向时应谨慎。然而,如果这些发现是真实的,那么该研究可能对预防老年人自杀具有重要意义,特别是在结核病流行率较高的国家。