Berlin NeuroImaging Center and Department Neurology, Charité, Berlin, Germany.
Magn Reson Imaging. 2009 Oct;27(8):1140-50. doi: 10.1016/j.mri.2009.04.001. Epub 2009 Jun 4.
Most functional neuroimaging studies have investigated brain activity evoked by certain types of stimulation or tasks. In recent years, resting brain activity and its influence on evoked activity has become accessible for investigation. However, despite numerous studies on background and evoked activities, either observed with vascular (functional magnetic resonance imaging, positron emission tomography, optical) or electrophysiological (electroencephalography, magnetoencephalography) or a combination of both methods, so far, there is no generally accepted view concerning both the precise meaning of background activity and its relationship to evoked activity. In this article, we give an overview of the current knowledge on this issue and we review recent studies examining the influence of ongoing activity on behavioral responses and the relationship between ongoing and evoked activity.
大多数功能神经影像学研究都调查了特定类型刺激或任务引起的大脑活动。近年来,静息大脑活动及其对诱发活动的影响已成为可研究的对象。然而,尽管有许多关于背景和诱发活动的研究,无论是通过血管(功能磁共振成像、正电子发射断层扫描、光学)还是电生理(脑电图、脑磁图)或两者结合的方法观察到的,到目前为止,对于背景活动的确切含义及其与诱发活动的关系,还没有一个普遍接受的观点。在本文中,我们概述了这一问题的现有知识,并回顾了最近研究正在进行的活动对行为反应的影响,以及正在进行的活动和诱发活动之间的关系。