Hinterberger W
I. Medizinischen Universitätsklinik Wien.
Wien Med Wochenschr. 1991;141(9-10):205-8.
Severe aplastic anemia is a rare disorder which is most often fatal when bone marrow transplantation or an immunosuppressive regimen is not applied. The cause of the disease in individual patients is not identifiable by laboratory investigations. The decision for a therapeutic modality is based on patient age and availability of an HLA-identical bone marrow donor. Early application of bone marrow transplantation may cure up to 80% of patients. Many patients may also be rescued with combined, intensive immunosuppression. Each of these treatment modalities, however, require early application, prior to the onset of typical complications such as infection and bleeding.
重型再生障碍性贫血是一种罕见的疾病，如果不进行骨髓移植或免疫抑制治疗，通常会致命。通过实验室检查无法确定个别患者的病因。治疗方式的选择基于患者年龄和 HLA 匹配的骨髓供体的可获得性。早期进行骨髓移植可治愈高达 80% 的患者。许多患者也可通过联合强化免疫抑制得到救治。然而，这些治疗方式中的每一种都需要在感染和出血等典型并发症出现之前尽早应用。
