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硬膜外分娩镇痛后行产时剖宫产的脊髓麻醉:一项回顾性队列研究。

Spinal anesthesia for intrapartum Cesarean delivery following epidural labor analgesia: a retrospective cohort study.

作者信息

Visser W Anton, Dijkstra Annemieke, Albayrak Mustafa, Gielen Mathieu J M, Boersma Eric, Vonsée Henk J

机构信息

Department of Anesthesiology, Intensive Care and Pain Management, Amphia Hospital, P.O. Box 90157, Breda 4800 RL, The Netherlands.

出版信息

Can J Anaesth. 2009 Aug;56(8):577-83. doi: 10.1007/s12630-009-9113-y. Epub 2009 Jun 5.

Abstract

PURPOSE

Failed conversion of epidural labor analgesia (ELA) to epidural surgical anesthesia (ESA) for intrapartum Cesarean delivery (CD) has been observed in clinical practice. However, spinal anesthesia (SA) in parturients experiencing failed conversion of ELA to ESA has been associated with an increased incidence of serious side effects. In this retrospective cohort analysis, we examined our routine clinical practice of removing the in situ epidural, rather than attempting to convert to ESA, prior to administering SA for intrapartum CD.

METHODS

Hemodynamic data, frequencies of either high or total spinal block, and maternal and neonatal outcome data were gathered from the anesthesia records of all parturients at the Amphia Hospital, undergoing intrapartum CD between January 1, 2001 and May 1, 2005.

RESULTS

Complete data were available for 693 patients (97.6%) of the 710 medical records that were identified. Of the 693 patients, 508 (73.3%) had no ELA and received SA, 128 patients (18.5%) received SA following epidural anesthesia for labor, 19 (2.7%) underwent conversion of ELA to ESA, and 38 (5.5%) received general anesthesia. When comparing both SA groups, no clinically relevant differences were observed regarding the incidence of total spinal block (0% in both groups) or high spinal block (0.2 vs 0.8%, P = 0.36). The number of hypotensive episodes, the total amount of ephedrine administered, and the Apgar scores recorded at 5 and 10 min were similar amongst groups.

CONCLUSIONS

The incidence of serious side effects associated with SA for intrapartum CD following ELA is low and not different compared to SA only.

摘要

目的

在临床实践中已观察到硬膜外分娩镇痛(ELA)转换为硬膜外手术麻醉(ESA)用于产时剖宫产(CD)失败的情况。然而,ELA转换为ESA失败的产妇接受脊髓麻醉(SA)与严重副作用发生率增加有关。在这项回顾性队列分析中,我们研究了在为产时CD实施SA之前,我们常规的临床做法是移除原位硬膜外导管,而不是试图转换为ESA。

方法

收集了2001年1月1日至2005年5月1日期间在安菲亚医院接受产时CD的所有产妇的麻醉记录中的血流动力学数据、高位或全脊髓阻滞的发生率以及母婴结局数据。

结果

在识别出的710份病历中,693例患者(97.6%)有完整数据。在这693例患者中,508例(73.3%)未接受ELA而接受了SA,128例患者(18.5%)在分娩硬膜外麻醉后接受了SA,19例(2.7%)ELA转换为ESA,38例(5.5%)接受了全身麻醉。比较两个SA组时,在全脊髓阻滞发生率(两组均为0%)或高位脊髓阻滞发生率(0.2%对0.8%,P = 0.36)方面未观察到临床相关差异。各组间低血压发作次数、麻黄碱使用总量以及5分钟和10分钟时记录的阿氏评分相似。

结论

ELA后产时CD接受SA相关的严重副作用发生率较低,与仅接受SA相比无差异。

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