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[吉布提出血性中风重症监护管理后的发病率和死亡率]

[Morbidity and mortality after intensive care management of hemorrhagic stroke in Djibouti].

作者信息

Benois A, Raynaud L, Coton T, Petitjeans F, Hassan A, Ilah A, Sergent H, Grassin F, Leberre J

机构信息

Service d'Anesthésie Réanimation, Groupement médico-chirurgical du Service de Santé des Armées, Bouffard, Djibouti.

出版信息

Med Trop (Mars). 2009 Feb;69(1):41-4.

Abstract

Prospective data on management and outcome of stroke in Africa is scarce. The purpose of this prospective descriptive study is to present epidemiologic, clinical and outcome data for a series of patients with hemorrhagic stroke in Djibouti. All patients admitted to the intensive care unit of the Bouffard Medical-Surgical Center in Djibouti for cerebral hemorrhage documented by CT-scan of the brain were recruited in this study. A total of 18 patients including 16 men were enrolled. The median patient age in this series was 51.5 years [range, 20-72]. The median duration of intensive care was 3 days [range, 1-38]. Mean Glasgow score at time of admission was 9 [range, 3-14]. Five patients were brought in by emergency medical airlift. The main risk factors for stroke were arterial hypertension, smoking, and regular khat use. Mechanical ventilation was performed in 10 patients with a survival rate of 40%. Six patients (33%) died in the intensive care unit. Hospital mortality within one month was 39% and mortality at 6 months was 44.4%. One-year survival for patients with a Glasgow score < or = 7 at the time of admission was 33%. Arterial hypertension, khat use, and smoking appeared to be major risk factors for male Djiboutians. Neurologic intensive care techniques provided hospital mortality rates similar to those reported in hospitals located in Western countries. Functional outcome in local survivors appeared to be good despite the absence of functional intensive care. These data argue against the passive, fatalistic approach to management of hemorrhagic stroke and for primary prevention of cardiovascular risk factors.

摘要

非洲地区关于中风管理和预后的前瞻性数据匮乏。这项前瞻性描述性研究的目的是呈现吉布提一系列出血性中风患者的流行病学、临床和预后数据。本研究纳入了所有因脑出血入住吉布提布法尔医疗外科中心重症监护病房且经脑部CT扫描确诊的患者。共招募了18名患者,其中包括16名男性。该系列患者的年龄中位数为51.5岁[范围为20 - 72岁]。重症监护的中位数时长为3天[范围为1 - 38天]。入院时的格拉斯哥评分平均为9分[范围为3 - 14分]。5名患者由紧急医疗空运送来。中风的主要危险因素为动脉高血压、吸烟和经常咀嚼巧茶。10名患者接受了机械通气,生存率为40%。6名患者(33%)在重症监护病房死亡。1个月内的医院死亡率为39%),6个月时的死亡率为44.4%。入院时格拉斯哥评分≤7分的患者1年生存率为33%。动脉高血压、咀嚼巧茶和吸烟似乎是吉布提男性的主要危险因素。神经重症监护技术所导致的医院死亡率与西方国家医院报告的死亡率相似。尽管缺乏功能强化护理,但当地幸存者的功能预后似乎良好。这些数据反对对出血性中风采取消极、宿命论的管理方式,并支持对心血管危险因素进行一级预防。

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