Faye O, Faye B, Ndiaye J L, Tine R C K, Ndiaye D, Haydara Mbacké A
Med Trop (Mars). 2009 Feb;69(1):101-2.
The purpose of this descriptive study conducted in an area endemic for lymphatic filariasis was to update information on the prevalence, clinical aspects, and awareness of this parasitic disease. All consenting inhabitants over 10 years old in three selected sectors were included. An entomological investigation was carried out to estimate the rate of vector infection. Out of a total of 3.359 subjects examined, 57.3% reported familiarity with the disease and provided an accurate description. The prevalence of clinical manifestations, i.e., mainly adenopathy, attributable to the disease was 14.11%. The overall prevalence rate of parasites was 4.7% with significant variations between sectors. The only parasite species found was Wuchereria bancrofti. Parasite load was low with 68.8% of subjects having less than 10 microfilariae per microliter of blood. Data analysis identified the following risk factors: age with 77.2% of microfilariae carriers over the age of 45 years, sex with 61.4% of carriers being female, and duration of residence in endemic area with 80.4% of carriers living in the area for more than 10 years. Differences were statistically significant. Dissection of 511 female culicidae showed no microfilariae carriers. These data indicate a declining ten-dency in this endemic zone in Senegal.
在淋巴丝虫病流行地区开展的这项描述性研究，旨在更新有关这种寄生虫病的患病率、临床症状及认知情况的信息。研究纳入了三个选定区域内所有10岁以上的自愿参与居民。开展了一项昆虫学调查以估计病媒感染率。在总共3359名接受检查的对象中，57.3%表示知晓该病并能给出准确描述。归因于该病的临床表现（主要为腺病）患病率为14.11%。寄生虫总体患病率为4.7%，各区域之间存在显著差异。发现的唯一寄生虫种类是班氏吴策线虫。寄生虫负荷较低，68.8%的对象每微升血液中微丝蚴少于10条。数据分析确定了以下风险因素：年龄方面，45岁以上的微丝蚴携带者占77.2%；性别方面，携带者中女性占61.4%；在流行地区的居住时长方面，80.4%的携带者在该地区居住超过10年。差异具有统计学意义。解剖511只雌性蚊科昆虫未发现微丝蚴携带者。这些数据表明塞内加尔这个流行区域的发病趋势呈下降态势。
