Role of magnesium in factor XIa catalyzed activation of factor IX: calcium binding to factor IX under physiologic magnesium.
作者信息
Agah S, Bajaj S P
出版信息
J Thromb Haemost. 2009 Aug;7(8):1426-8. doi: 10.1111/j.1538-7836.2009.03506.x. Epub 2009 Jun 3.
Abstract
摘要
相似文献
1
Role of magnesium in factor XIa catalyzed activation of factor IX: calcium binding to factor IX under physiologic magnesium.镁在因子XIa催化因子IX激活中的作用：生理镁浓度下钙与因子IX的结合
J Thromb Haemost. 2009 Aug;7(8):1426-8. doi: 10.1111/j.1538-7836.2009.03506.x. Epub 2009 Jun 3.
2
Modification of the N-terminus of human factor IX by defective propeptide cleavage or acetylation results in a destabilized calcium-induced conformation: effects on phospholipid binding and activation by factor XIa.人凝血因子IX的N端通过缺陷性前肽切割或乙酰化修饰会导致钙诱导构象不稳定：对磷脂结合和因子XIa激活的影响。
Biochem J. 1997 May 1;323 ( Pt 3)(Pt 3):629-36. doi: 10.1042/bj3230629.
3
Exosite-mediated substrate recognition of factor IX by factor XIa. The factor XIa heavy chain is required for initial recognition of factor IX.因子 XIa 通过外部位点介导的对因子 IX 的底物识别。因子 XIa 的重链是识别因子 IX 所必需的。
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4
Identification and chemical synthesis of a substrate-binding site for factor IX on coagulation factor XIa.凝血因子XIa上因子IX底物结合位点的鉴定与化学合成
J Biol Chem. 1991 Dec 15;266(35):24190-7.
5
The factor IX phospholipid-binding site is required for calcium-dependent activation of factor IX by factor XIa.
J Biol Chem. 1987 Jun 5;262(16):7605-12.
6
First epidermal growth factor-like domain of human blood coagulation factor IX is required for its activation by factor VIIa/tissue factor but not by factor XIa.人凝血因子IX的首个表皮生长因子样结构域是其被因子VIIa/组织因子激活所必需的，但不是被因子XIa激活所必需的。
Proc Natl Acad Sci U S A. 1994 Apr 26;91(9):3574-8. doi: 10.1073/pnas.91.9.3574.
7
Factor IX activation by factor XIa proceeds without release of a free intermediate.因子 XIa 激活因子 IX 的过程中不会释放游离中间体。
Biochemistry. 1997 Apr 8;36(14):4074-9. doi: 10.1021/bi962274y.
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Identification of a factor IX binding site on the third apple domain of activated factor XI.活化因子XI第三个苹果结构域上因子IX结合位点的鉴定。
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Substrate-dependent modulation of the mechanism of factor XIa inhibition.凝血因子XIa抑制机制的底物依赖性调节
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The factor IX gamma-carboxyglutamic acid (Gla) domain is involved in interactions between factor IX and factor XIa.凝血因子IX的γ-羧基谷氨酸（Gla）结构域参与凝血因子IX与凝血因子XIa之间的相互作用。
J Biol Chem. 2003 Mar 7;278(10):7981-7. doi: 10.1074/jbc.M212748200. Epub 2002 Dec 20.
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Taking the thrombin "fork".采用凝血酶“叉”。
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Contribution of magnesium in binding of factor IXa to the phospholipid surface: implications for vitamin K-dependent coagulation proteins.镁在因子IXa与磷脂表面结合中的作用：对维生素K依赖性凝血蛋白的影响。
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本文引用的文献
1
Substitution of the Gla domain in factor X with that of protein C impairs its interaction with factor VIIa/tissue factor: lack of comparable effect by similar substitution in factor IX.将因子X中的γ-羧基谷氨酸（Gla）结构域替换为蛋白C的Gla结构域会损害其与因子VIIa/组织因子的相互作用：因子IX中类似替换缺乏可比效应。
J Biol Chem. 2007 May 25;282(21):15632-44. doi: 10.1074/jbc.M701908200. Epub 2007 Mar 26.
2
High resolution structures of p-aminobenzamidine- and benzamidine-VIIa/soluble tissue factor: unpredicted conformation of the 192-193 peptide bond and mapping of Ca2+, Mg2+, Na+, and Zn2+ sites in factor VIIa.对氨基苯甲脒和苯甲脒-VIIa/可溶性组织因子的高分辨率结构：192-193肽键的意外构象以及因子VIIa中Ca2+、Mg2+、Na+和Zn2+位点的定位
J Biol Chem. 2006 Aug 25;281(34):24873-88. doi: 10.1074/jbc.M509971200. Epub 2006 Jun 6.
3
The extended interactions and Gla domain of blood coagulation factor Xa.凝血因子Xa的扩展相互作用和Gla结构域。
Biochemistry. 2003 Jul 8;42(26):7959-66. doi: 10.1021/bi027320a.
4
Crystal structure of Mg2+- and Ca2+-bound Gla domain of factor IX complexed with binding protein.与结合蛋白复合的凝血因子IX的Mg2+和Ca2+结合Gla结构域的晶体结构
J Biol Chem. 2003 Jun 27;278(26):24090-4. doi: 10.1074/jbc.M300650200. Epub 2003 Apr 14.
5
Structure-function relationships in factor IX and factor IXa.凝血因子IX与活化凝血因子IX的结构-功能关系
Trends Cardiovasc Med. 2003 Jan;13(1):39-45. doi: 10.1016/s1050-1738(02)00210-4.
6
The factor IX gamma-carboxyglutamic acid (Gla) domain is involved in interactions between factor IX and factor XIa.凝血因子IX的γ-羧基谷氨酸（Gla）结构域参与凝血因子IX与凝血因子XIa之间的相互作用。
J Biol Chem. 2003 Mar 7;278(10):7981-7. doi: 10.1074/jbc.M212748200. Epub 2002 Dec 20.
7
pH effects on measurements of ionized calcium and ionized magnesium in blood.pH值对血液中离子钙和离子镁测量的影响。
Arch Pathol Lab Med. 2002 Aug;126(8):947-50. doi: 10.5858/2002-126-0947-PEOMOI.
8
Identification of the phospholipid binding site in the vitamin K-dependent blood coagulation protein factor IX.维生素K依赖性血液凝固蛋白因子IX中磷脂结合位点的鉴定。
J Biol Chem. 1996 Jul 5;271(27):16227-36. doi: 10.1074/jbc.271.27.16227.
9
Human factor IX and factor IXa.人凝血因子IX和凝血因子IXa。
Methods Enzymol. 1993;222:96-128. doi: 10.1016/0076-6879(93)22009-5.
10
Regulation of the tertiary structure and function of coagulation factor IX by magnesium (II) ions.
J Biol Chem. 1995 Jun 16;270(24):14325-31. doi: 10.1074/jbc.270.24.14325.
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