人嗜 T 细胞病毒 1 型感染患者中的次发性粪类圆线虫病预防：两例报告。

Secondary Strongyloides stercoralis prophylaxis in patients with human T-cell lymphotropic virus type 1 infection: report of two cases.

机构信息

Postgraduate Training Program, Division of Infectious Diseases, University of British Columbia, Vancouver, Canada.

出版信息

Int J Infect Dis. 2009 Nov;13(6):e501-3. doi: 10.1016/j.ijid.2009.02.009. Epub 2009 Jun 4.

DOI:10.1016/j.ijid.2009.02.009

PMID:19501008

Abstract

Secondary ivermectin prophylaxis for strongyloidiasis in two patients with human T-cell lymphotropic virus type 1 (HTLV-1)-associated malignancies and fully treated complicated strongyloidiasis is described. Treatment was well tolerated and neither patient developed further manifestations of hyperinfection. As treatment failure for complicated strongyloidiasis has been documented in severely immunosuppressed patients, secondary prophylaxis may be indicated.

摘要

本文描述了两例人类 T 细胞白血病病毒 1 型（HTLV-1）相关恶性肿瘤合并完全治疗的复杂性粪类圆线虫病患者，采用伊维菌素进行二级预防。治疗耐受性良好，两名患者均未出现进一步的感染加重表现。由于严重免疫抑制患者中曾有治疗失败的复杂性粪类圆线虫病病例报道，因此可能需要二级预防。