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盐味敏感阈值与运动性高血压

Salt taste sensitivity threshold and exercise-induced hypertension.

作者信息

Rabin Mendel, Poli de Figueiredo Carlos Eduardo, Wagner Mario Bernardes, Antonello Ivan Carlos Ferreira

机构信息

Programa de Pós-graduação em Medicina e Ciências da Saúde (Nefrologia), Laboratório de Nefrologia, IPB/HSL/FAMED, Brazil; Cardiology Department Ergometry Unit, Pontifícia Universidade Católica do Rio Grande do Sul. Porto Alegre, Brazil.

Programa de Pós-graduação em Medicina e Ciências da Saúde (Nefrologia), Laboratório de Nefrologia, IPB/HSL/FAMED, Brazil.

出版信息

Appetite. 2009 Jun;52(3):609-613. doi: 10.1016/j.appet.2009.02.007. Epub 2009 Feb 25.

Abstract

Salt taste sensitivity is the capacity to identify the flavour of salt. It is possible that salt taste sensitivity threshold (STST) can influence salt appetite, and sodium ingestion is associated with hypertension. The present study evaluates the relationship between salt taste sensitivity threshold (STST) and blood pressure (BP) response to exercise during a treadmill stress test. Two hundred and three normotensive individuals undergoing evaluation before starting an exercise training program were tested for STST, using concentrated saline solutions from 0.22 to 58.4g/L. Patients were divided into two groups according to the STST: normal (n-STST) and increased (i-STST); and into two groups according to their BP response to exercise: exercise-induced hypertension (EIH) or physiological blood pressure response (n-EIH). EIH was detected in 49 (24.1%) individuals. Initial systolic and diastolic BP and their areas under the curves during the test were higher in the EIH group. Initial systolic and diastolic BP areas under the curves were significantly higher in i-STST than n-STST. There was an association between STST of at least 1.8g/L (increased STST) and EIH (OR=6.71, 95% CI 1.5-29.99) independent of gender, body mass index and age. Occurrence of EIH was associated to i-STST, suggesting that a relationship between high STST and increased BP response to exercise is possible.

摘要

盐味敏感性是识别盐味的能力。盐味敏感阈值(STST)可能会影响盐食欲,并且钠摄入与高血压有关。本研究评估了在跑步机压力测试期间盐味敏感阈值(STST)与运动时血压(BP)反应之间的关系。对203名在开始运动训练计划前接受评估的血压正常个体进行了STST测试,使用浓度为0.22至58.4g/L的浓缩盐溶液。根据STST将患者分为两组:正常(n-STST)和升高(i-STST);并根据他们对运动的血压反应分为两组:运动性高血压(EIH)或生理性血压反应(n-EIH)。在49名(24.1%)个体中检测到EIH。EIH组的初始收缩压和舒张压及其测试期间的曲线下面积更高。i-STST组的初始收缩压和舒张压曲线下面积显著高于n-STST组。STST至少为1.8g/L(升高的STST)与EIH之间存在关联(OR=6.71,95%CI 1.5-29.99),与性别、体重指数和年龄无关。EIH的发生与i-STST相关,表明高STST与运动时血压反应增加之间可能存在关联。

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