Creran Brian, Li Xiaoning, Duncan Bradley, Kim Chang Soo, Moyano Daniel F, Rotello Vincent M
Department of Chemistry, University of Massachusetts , Amherst, Massachusetts 01003, United States.
ACS Appl Mater Interfaces. 2014 Nov 26;6(22):19525-30. doi: 10.1021/am505689g. Epub 2014 Oct 30.
Low-cost diagnostics for drinking water contamination have the potential to save millions of lives. We report a method that uses inkjet printing to copattern an enzyme-nanoparticle sensor and substrate on a paper-based test strip for rapid detection of bacteria. A colorimetric response is generated on the paper substrate that allows visual detection of contamination without the need for expensive instrumentation. These strips demonstrate a viable nanomanufacturing strategy for low-cost bacterial detection.
用于检测饮用水污染的低成本诊断方法有潜力挽救数百万人的生命。我们报告了一种方法,该方法利用喷墨印刷技术在纸质测试条上共同图案化酶-纳米颗粒传感器和底物,以快速检测细菌。在纸质底物上产生比色反应,无需昂贵的仪器即可实现对污染的视觉检测。这些测试条展示了一种用于低成本细菌检测的可行的纳米制造策略。