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麻醉与心肌缺血/再灌注损伤。

Anaesthesia and myocardial ischaemia/reperfusion injury.

作者信息

Frässdorf J, De Hert S, Schlack W

机构信息

Departement of Anesthesiology, AMC-University of Amsterdam, Meibergdreef 9, Amsterdam, The Netherlands.

出版信息

Br J Anaesth. 2009 Jul;103(1):89-98. doi: 10.1093/bja/aep141. Epub 2009 Jun 5.

Abstract

Anaesthetists are confronted on a daily basis with patients with coronary artery disease, myocardial ischaemia, or both during the perioperative period. Therefore, prevention and ultimately adequate therapy of perioperative myocardial ischaemia and its consequences are the major challenges in current anaesthetic practice. This review will focus on the translation of the laboratory evidence of anaesthetic-induced cardioprotection into daily clinical practice.

摘要

麻醉医生在围手术期每天都会面对患有冠状动脉疾病、心肌缺血或两者皆有的患者。因此,围手术期心肌缺血及其后果的预防以及最终的充分治疗是当前麻醉实践中的主要挑战。本综述将重点关注麻醉诱导的心脏保护的实验室证据转化为日常临床实践。

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