七氟烷吸入麻醉的临床综述：从早期研究到新兴话题
A clinical review of inhalation anesthesia with sevoflurane: from early research to emerging topics.
作者信息
Brioni Jorge D, Varughese Shane, Ahmed Raza, Bein Berthold
机构信息
Global Medical Affairs, AbbVie, Inc., 1 N. Waukegan Rd., ABV1, North Chicago, IL, 60064, USA.
Asklepios Hospital St. Georg, Lohmühlenstraße 5, D-20099, Hamburg, Germany.
出版信息
J Anesth. 2017 Oct;31(5):764-778. doi: 10.1007/s00540-017-2375-6. Epub 2017 Jun 5.
Abstract
A large number of studies during the past two decades have demonstrated the efficacy and safety of sevoflurane across patient populations. Clinical researchers have also investigated the effects of sevoflurane, its hemodynamic characteristics, its potential protective effects on several organ systems, and the incidence of delirium and cognitive deficiency. This review examines the clinical profiles of sevoflurane and other anesthetic agents, and focuses upon emerging topics such as organ protection, postoperative cognitive deficiency and delirium, and novel ways to improve postanesthesia outcomes.
摘要
在过去二十年中，大量研究已证明七氟醚在各类患者群体中的有效性和安全性。临床研究人员还研究了七氟醚的作用、其血流动力学特征、对多个器官系统的潜在保护作用以及谵妄和认知缺陷的发生率。本综述考察了七氟醚及其他麻醉剂的临床概况，并着重探讨了诸如器官保护、术后认知缺陷和谵妄等新出现的课题，以及改善麻醉后转归的新方法。
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