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[脲原体在兔实验性感染中的持续存在及其致关节炎作用]

[The persistence of Ureaplasma and its arthritogenic action in the experimental infection of rabbits].

作者信息

Vul'fovich Iu V, Gamova N A, Zul'fian A V

出版信息

Zh Mikrobiol Epidemiol Immunobiol. 1991 Jul(7):20-2.

PMID:1950258
Abstract

In the experimental intraperitoneal infection of rabbits with U. urealyticum, serotype VIII, transitory polyarthritis with immunomorphological characteristics different from those of human rheumatoid arthritis has been shown to develop in the animals. The pathological process develops simultaneously with Ureaplasma infection. U. urealyticum persists in the body of infected rabbits during 12 weeks of observation. The mechanism of the resorption process in the bone tissue of joints, running similarly to periosteocytic osteolysis, is discussed.

摘要

在用解脲脲原体血清型VIII对兔子进行实验性腹腔感染时,已证实动物会出现具有不同于人类类风湿性关节炎免疫形态学特征的短暂性多关节炎。病理过程与脲原体感染同时发生。在12周的观察期内,解脲脲原体在受感染兔子体内持续存在。文中讨论了关节骨组织中吸收过程的机制,该过程与骨细胞周围性骨质溶解类似。

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