Silverman J F, Gurley A M, Harris J P, Weaver M D, Bernacki E G
Department of Pathology, East Carolina University School of Medicine, Greenville, North Carolina 27858-4354.
Acta Cytol. 1991 Nov-Dec;35(6):736-41.
The fine needle aspiration (FNA) cytologic features of two cases of renal infarction are presented. Both patients did not have a classic clinical history for infarction, and the radiologic findings were suggestive of neoplasia. In one of our cases, necrotic glomeruli and tubules were present, which suggested the correct diagnosis of renal infarction and permitted appropriate early treatment. In the other case, groups of atypical renal tubular cells undergoing repair secondary to the infarction was misinterpreted as renal cell carcinoma. This case illustrates that renal infarction, like pulmonary infarction, can be a potential pitfall for a false-positive cytologic diagnosis of malignancy in FNA biopsy. A conservative approach is warranted when there is scanty cellularity and atypical cells having features of a repairlike reaction are present.
本文介绍了两例肾梗死的细针穿刺(FNA)细胞学特征。两名患者均无典型的梗死临床病史,影像学检查结果提示为肿瘤。在我们的其中一例病例中,存在坏死的肾小球和肾小管,这提示了肾梗死的正确诊断,并得以进行适当的早期治疗。在另一例病例中,梗死继发修复过程中出现的一组非典型肾小管细胞被误诊为肾细胞癌。该病例表明,肾梗死与肺梗死一样,在FNA活检中可能是导致恶性肿瘤细胞学诊断假阳性的潜在陷阱。当细胞数量稀少且存在具有修复样反应特征的非典型细胞时,采用保守方法是必要的。