患有IV-S期神经母细胞瘤的婴儿中模仿常见急性淋巴细胞白血病的骨髓细胞群。
Bone marrow cell populations mimicking common acute lymphoblastic leukemia in infants with stage IV-S neuroblastoma.
作者信息
Mandel M, Rechavi G, Neumann Y, Biniaminov M, Brok-Simoni F, Bojanover Y, Burstein Y, Ben-Bassat I, Ramot B
机构信息
Institute of Hematology, Chaim Sheba Medical Center, Tel Hashomer, Israel.
出版信息
Acta Haematol. 1991;86(2):86-9. doi: 10.1159/000204809.
Immunophenotyping of bone marrow mononuclear cells of 2 infants with stage IV-S neuroblastoma revealed the presence of many lymphoblasts and immature lymphocytes. Immunophenotyping showed that a high percentage of bone marrow cells were positive for the HLA-DR, CD19, CD20 and CD10 phenotype, similar to common acute lymphoblastic leukemia cells. Within 6 months of follow-up, without any treatment, complete regression of the tumors was observed. The coexistence of these two unusual populations will be discussed.
对2例IV-S期神经母细胞瘤婴儿的骨髓单个核细胞进行免疫表型分析，结果显示存在许多淋巴母细胞和未成熟淋巴细胞。免疫表型分析表明，高比例的骨髓细胞对HLA-DR、CD19、CD20和CD10表型呈阳性，类似于常见的急性淋巴细胞白血病细胞。在随访的6个月内，未经任何治疗，肿瘤出现完全消退。将对这两种异常细胞群的共存情况进行讨论。
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