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门诊烧伤患者中的耐甲氧西林金黄色葡萄球菌疖病

Methicillin-resistant Staphylococcus aureus furunculitis in the outpatient burn setting.

作者信息

Warner Petra, Neely Alice, Bailey J Kevin, Yakuboff Kevin P, Kagan Richard J

机构信息

Shriners Hospitals for Children, and University of Cincinnati, Cincinnati, Ohio 45229, USA.

出版信息

J Burn Care Res. 2009 Jul-Aug;30(4):657-60. doi: 10.1097/BCR.0b013e3181abff56.

DOI:10.1097/BCR.0b013e3181abff56
PMID:19506501
Abstract

Methicillin-resistant Staphylococcus aureus (MRSA) is becoming more predominant in the community. We have seen increasing cases of furunculitis in our outpatient burn clinic, which appear to develop weeks after the initial burn injury and in patients with limited inpatient stays. We performed a 3-year retrospective review of all outpatient burn patients who developed furunculitis. Data analyzed included length of hospital stay, type of injury sustained, culture and sensitivity results, and treatment provided. A total of 28 patients were identified with MRSA furunculitis, which presented as painful, hard, indurated boils with minimal purulent drainage. Adults had less extensive burn injuries (mean of 12% TBSA adults vs 20% TBSA children) with shorter hospital stays (mean 8 days adults vs 22 days children). Fifty-seven percent of the patients had multiple furuncules, involving both burned and nonburned areas. Patients with furunculitis had a less resistant MRSA strain than those without furunculitis. Of the 22 patients who received systemic antibiotic coverage, 14 (58%) were successfully treated with 1 antibiotic regimen, whereas 8 (33%) required multiple antibiotics. In this study, furunculitis in the outpatient setting was believed to be consistent with community-acquired MRSA. Incision and drainage was not sufficient in patients with multiple furuncles, and systemic antibiotics were administered. Through increased awareness of the prevalence of community-acquired MRSA in the community, appropriate antibiotic treatment can be initiated, and the discomfort and transmission risk associated with this disease can be minimized.

摘要

耐甲氧西林金黄色葡萄球菌(MRSA)在社区中日益占主导地位。我们在门诊烧伤诊所看到疖病病例不断增加,这些病例似乎在初次烧伤数周后出现,且多见于住院时间有限的患者。我们对所有发生疖病的门诊烧伤患者进行了为期3年的回顾性研究。分析的数据包括住院时间、受伤类型、培养及药敏结果以及所提供的治疗。共确定28例患有MRSA疖病的患者,其表现为疼痛、坚硬、硬结的疖肿,伴有少量脓性分泌物。成人烧伤面积较小(成人平均体表面积为12%,儿童为20%),住院时间较短(成人平均8天,儿童22天)。57%的患者有多个疖肿,累及烧伤和未烧伤区域。患有疖病的患者的MRSA菌株耐药性低于未患疖病的患者。在22例接受全身抗生素治疗的患者中,14例(58%)经1种抗生素治疗成功,而8例(33%)需要多种抗生素治疗。在本研究中,门诊环境中的疖病被认为与社区获得性MRSA一致。对于有多个疖肿的患者,切开引流并不充分,需给予全身抗生素治疗。通过提高对社区获得性MRSA在社区中流行情况的认识,可以启动适当的抗生素治疗,并将与该疾病相关的不适和传播风险降至最低。

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