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[经尿道膀胱肿瘤电切术后辅助化疗和放疗有效治疗膀胱小细胞癌病例]

[Case of small cell carcinoma of the urinary bladder effectively treated with adjuvant chemotherapy and radiotherapy following TUR].

作者信息

Okuda Yasuto, Mori Yasunori, Katoh Yoshinari, Iguchi Masanori, Katoh Mitsuru, Yamazaki Dai

机构信息

Department of Urology, Kaizuka City Hospital.

出版信息

Hinyokika Kiyo. 2009 May;55(5):267-9.

PMID:19507545
Abstract

A 82-year-old man was referred to our hospital with a chief complaint of macrohematuria and pollakisuria. Cystoscopy showed an abnormal mucosa on the right wall. We suspected carcinoma in situ but two months after cystoscopy showed a non-papillary and sessile tumor with calcification. We performed transurethral resection of the bladder tumor, muscle layer and adipose tissue. Histopathological findings revealed small cell carcinoma of the bladder infiltrating the externaladipose tissue. As postoperative adjuvant therapy, chemotherapy (cisplatin total 150 mg) was performed with 40 Gy of extra beam radiotherapy to the bladder. After chemotherapy and radiotherapy,urinary cytology was negative and cystoscopy showed the scar. Follow up magnetic resonance imaging revealed disappearance of the bladder tumor.

摘要

一名82岁男性因肉眼血尿和尿频为主诉被转诊至我院。膀胱镜检查显示右侧壁黏膜异常。我们怀疑是原位癌,但膀胱镜检查两个月后显示为非乳头状、无蒂且伴有钙化的肿瘤。我们进行了经尿道膀胱肿瘤、肌层及脂肪组织切除术。组织病理学检查结果显示为膀胱小细胞癌浸润至膀胱外脂肪组织。作为术后辅助治疗,给予化疗(顺铂总量150mg),并对膀胱进行40Gy的体外照射放疗。化疗和放疗后,尿细胞学检查为阴性,膀胱镜检查显示为瘢痕。随访磁共振成像显示膀胱肿瘤消失。

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