Kulzer Bernhard, Hermanns Norbert, Gorges Daniela, Schwarz Peter, Haak Thomas
Research Institute of the Diabetes Academy Mergentheim and Diabetes Centre Mergentheim, Bad Mergentheim, Germany.
Diabetes Care. 2009 Jul;32(7):1143-6. doi: 10.2337/dc08-2141. Epub 2009 Jun 9.
To evaluate the efficacy of the group program PREDIAS for diabetes prevention.
PREDIAS consists of 12 lessons and aims at lifestyle modification. The control group received written information about diabetes prevention. In this study, a total of 182 persons with an elevated diabetes risk participated (aged 56.3 +/- 10.1 years, 43% female, and BMI 31.5 +/- 5.3 kg/m(2)).
After 12 months, weight loss was significantly higher (P = 0.001) in PREDIAS than in the control group (-3.8 +/- 5.2 vs. -1.4 +/- 4.09 kg). There were also significant effects (P = 0.001) on fasting glucose (control group 1.8 +/- 13.1 mg/dl vs. PREDIAS -4.3 +/- 11.3 mg/dl), duration of physical activity per week (control group 17.9 +/- 63.8 min vs. PREDIAS 46.6 +/- 95.5 min; P = 0.03), and eating behavior.
PREDIAS significantly modified lifestyle factors associated with an elevated diabetes risk.
评估PREDIAS团体项目预防糖尿病的疗效。
PREDIAS包括12节课程,旨在改变生活方式。对照组收到关于糖尿病预防的书面信息。在本研究中,共有182名糖尿病风险升高的人参与(年龄56.3±10.1岁,43%为女性,体重指数31.5±5.3kg/m²)。
12个月后,PREDIAS组的体重减轻显著高于对照组(P = 0.001)(-3.8±5.2 vs. -1.4±4.09kg)。空腹血糖(对照组1.8±13.1mg/dl vs. PREDIAS组-4.3±11.3mg/dl)、每周体育活动时长(对照组17.9±63.8分钟 vs. PREDIAS组46.6±95.5分钟;P = 0.03)和饮食行为也有显著变化(P = 0.001)。
PREDIAS显著改变了与糖尿病风险升高相关的生活方式因素。