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Exercise or exercise and diet for preventing type 2 diabetes mellitus.运动或运动与饮食对预防2型糖尿病的作用
Cochrane Database Syst Rev. 2008 Jul 16(3):CD003054. doi: 10.1002/14651858.CD003054.pub3.
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Development of a diabetes prevention management program for clinical practice.用于临床实践的糖尿病预防管理项目的开发。
Public Health Rep. 2007 Mar-Apr;122(2):258-63. doi: 10.1177/003335490712200216.
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Pharmacological and lifestyle interventions to prevent or delay type 2 diabetes in people with impaired glucose tolerance: systematic review and meta-analysis.预防或延缓糖耐量受损人群发生2型糖尿病的药物及生活方式干预:系统评价与荟萃分析
BMJ. 2007 Feb 10;334(7588):299. doi: 10.1136/bmj.39063.689375.55. Epub 2007 Jan 19.
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The diabetes risk score: a practical tool to predict type 2 diabetes risk.糖尿病风险评分:一种预测2型糖尿病风险的实用工具。
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The Diabetes Prevention Program (DPP): description of lifestyle intervention.糖尿病预防计划(DPP):生活方式干预的描述
Diabetes Care. 2002 Dec;25(12):2165-71. doi: 10.2337/diacare.25.12.2165.
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Reduction in the incidence of type 2 diabetes with lifestyle intervention or metformin.通过生活方式干预或二甲双胍降低2型糖尿病的发病率。
N Engl J Med. 2002 Feb 7;346(6):393-403. doi: 10.1056/NEJMoa012512.
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Prevention of type 2 diabetes mellitus by changes in lifestyle among subjects with impaired glucose tolerance.糖耐量受损人群通过生活方式改变预防2型糖尿病
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糖尿病自我管理预防项目(PREDIAS):对体重、代谢风险因素及行为结果的影响。

Prevention of diabetes self-management program (PREDIAS): effects on weight, metabolic risk factors, and behavioral outcomes.

作者信息

Kulzer Bernhard, Hermanns Norbert, Gorges Daniela, Schwarz Peter, Haak Thomas

机构信息

Research Institute of the Diabetes Academy Mergentheim and Diabetes Centre Mergentheim, Bad Mergentheim, Germany.

出版信息

Diabetes Care. 2009 Jul;32(7):1143-6. doi: 10.2337/dc08-2141. Epub 2009 Jun 9.

DOI:10.2337/dc08-2141
PMID:19509014
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2699739/
Abstract

OBJECTIVE

To evaluate the efficacy of the group program PREDIAS for diabetes prevention.

RESEARCH DESIGN AND METHODS

PREDIAS consists of 12 lessons and aims at lifestyle modification. The control group received written information about diabetes prevention. In this study, a total of 182 persons with an elevated diabetes risk participated (aged 56.3 +/- 10.1 years, 43% female, and BMI 31.5 +/- 5.3 kg/m(2)).

RESULTS

After 12 months, weight loss was significantly higher (P = 0.001) in PREDIAS than in the control group (-3.8 +/- 5.2 vs. -1.4 +/- 4.09 kg). There were also significant effects (P = 0.001) on fasting glucose (control group 1.8 +/- 13.1 mg/dl vs. PREDIAS -4.3 +/- 11.3 mg/dl), duration of physical activity per week (control group 17.9 +/- 63.8 min vs. PREDIAS 46.6 +/- 95.5 min; P = 0.03), and eating behavior.

CONCLUSIONS

PREDIAS significantly modified lifestyle factors associated with an elevated diabetes risk.

摘要

目的

评估PREDIAS团体项目预防糖尿病的疗效。

研究设计与方法

PREDIAS包括12节课程,旨在改变生活方式。对照组收到关于糖尿病预防的书面信息。在本研究中,共有182名糖尿病风险升高的人参与(年龄56.3±10.1岁,43%为女性,体重指数31.5±5.3kg/m²)。

结果

12个月后,PREDIAS组的体重减轻显著高于对照组(P = 0.001)(-3.8±5.2 vs. -1.4±4.09kg)。空腹血糖(对照组1.8±13.1mg/dl vs. PREDIAS组-4.3±11.3mg/dl)、每周体育活动时长(对照组17.9±63.8分钟 vs. PREDIAS组46.6±95.5分钟;P = 0.03)和饮食行为也有显著变化(P = 0.001)。

结论

PREDIAS显著改变了与糖尿病风险升高相关的生活方式因素。