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意大利新兵中A群和C群脑膜炎奈瑟菌荚膜多糖疫苗的血清抗体情况

Serum antibodies to capsular polysaccharide vaccine of group A and C Neisseria meningitidis in military recruits in Italy.

作者信息

Occhionero M, Usai G, Di Martino M, Le Moli S, Stroffolini T, Mastrantonio P

机构信息

Laboratorio di Batteriologia e Micologia Medica, Istituto Superiore di Sanità, Roma.

出版信息

Allergol Immunopathol (Madr). 1991 Jan-Feb;19(1):39-41.

PMID:1950941
Abstract

In this study we evaluated, by a standard bactericidal assay, the antibody response to the meningococcal group A and C polysaccharide vaccine used for the immunization programme of the Italian military recruits, compulsory by law since 1987. The percentage of responders, those who developed a four-fold increase in the bactericidal titre to polysaccharide A and C, was 96% and 98%, respectively. No significant side effects were observed after vaccination.

摘要

在本研究中,我们通过标准杀菌试验评估了自1987年起依法强制用于意大利新兵免疫计划的A群和C群脑膜炎球菌多糖疫苗的抗体反应。对多糖A和C杀菌效价升高四倍的应答者百分比分别为96%和98%。接种疫苗后未观察到明显的副作用。

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Serum antibodies to capsular polysaccharide vaccine of group A and C Neisseria meningitidis in military recruits in Italy.意大利新兵中A群和C群脑膜炎奈瑟菌荚膜多糖疫苗的血清抗体情况
Allergol Immunopathol (Madr). 1991 Jan-Feb;19(1):39-41.
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Analysis of the ontogeny of the murine humoral response to Neisseria meningitidis B capsular polysaccharide reveals levels of complexity relevant to vaccine development.对小鼠针对B型脑膜炎奈瑟菌荚膜多糖的体液免疫反应个体发生的分析揭示了与疫苗开发相关的复杂程度。
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