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意大利新兵中A群和C群脑膜炎奈瑟菌荚膜多糖疫苗的血清抗体情况

Serum antibodies to capsular polysaccharide vaccine of group A and C Neisseria meningitidis in military recruits in Italy.

作者信息

Occhionero M, Usai G, Di Martino M, Le Moli S, Stroffolini T, Mastrantonio P

机构信息

Laboratorio di Batteriologia e Micologia Medica, Istituto Superiore di Sanità, Roma.

出版信息

Allergol Immunopathol (Madr). 1991 Jan-Feb;19(1):39-41.

PMID:1950941
Abstract

In this study we evaluated, by a standard bactericidal assay, the antibody response to the meningococcal group A and C polysaccharide vaccine used for the immunization programme of the Italian military recruits, compulsory by law since 1987. The percentage of responders, those who developed a four-fold increase in the bactericidal titre to polysaccharide A and C, was 96% and 98%, respectively. No significant side effects were observed after vaccination.

摘要

在本研究中,我们通过标准杀菌试验评估了自1987年起依法强制用于意大利新兵免疫计划的A群和C群脑膜炎球菌多糖疫苗的抗体反应。对多糖A和C杀菌效价升高四倍的应答者百分比分别为96%和98%。接种疫苗后未观察到明显的副作用。

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