Lord J A, Waterfield A A, Hughes J, Kosterlitz H W
Nature. 1977 Jun 9;267(5611):495-9. doi: 10.1038/267495a0.
Opioid peptides were assayed by inhibition of 3H-naloxone and 3H-leu-enkephalin binding in brain homogenates and by depression of contractions of the guinea pig ileum and mouse vas deferens. We conclude that the opioid peptidergic system has agonists of different characteristics which interact with more than one type of receptor.
通过抑制脑匀浆中3H-纳洛酮和3H-亮氨酸脑啡肽的结合以及通过抑制豚鼠回肠和小鼠输精管的收缩来测定阿片肽。我们得出结论，阿片肽能系统具有不同特性的激动剂，它们与不止一种类型的受体相互作用。
