Rolf N, Coté C J
Department of Anaesthesia, Harvard Medical School, Massachusetts General Hospital, Boston 02114.
Anesth Analg. 1991 Dec;73(6):720-4. doi: 10.1213/00000539-199112000-00008.
The presence of persistent arrhythmias was correlated with hypercarbia (end-tidal CO2 greater than or equal to 55 mm Hg for greater than or equal to 60 s). A continuous strip chart recording of oxygen saturation, a capnogram, and an electrocardiogram were obtained from 402 children. No episodes of arrhythmia occurred in 153 patients younger than 2 yr compared with 24 patients 2 yr of age or older (P = 0.0001). Older patients whose airways were managed via a mask had a higher incidence (13.2% [21 of 159 patients]) than tracheally intubated patients (3.3% [3 of 90 patients]) (P = 0.01). In older patients whose tracheas were intubated, hypercarbia was associated with arrhythmia in 1 of 20 hypercarbia episodes. Seven of 16 patients with hypercarbia, whose airways were managed via a mask, had an arrhythmia (P = 0.0014); in eight, arrhythmias were associated with light anesthesia; in seven, arrhythmias were not associated with either hypercarbia or light anesthesia. Arrhythmias developed in 13 of 55 patients 2 yr old or older whose airways were managed via a mask and who were undergoing orchiopexy or herniorrhaphy as compared with 1 of 30 tracheally intubated patients (P = 0.016). There was a higher incidence of arrhythmias during halothane anesthesia compared with that during all other techniques (P = 0.035). The authors conclude that the incidence of arrhythmias is extremely low in infants younger than 2 yr. Hypercarbia is associated with arrhythmias in pediatric patients whose airways are managed via a mask but not in patients whose tracheas are intubated.(ABSTRACT TRUNCATED AT 250 WORDS)
持续性心律失常的出现与高碳酸血症相关(呼气末二氧化碳分压大于或等于55 mmHg持续大于或等于60秒)。对402名儿童进行了氧饱和度、二氧化碳波形图和心电图的连续长条图记录。153名2岁以下的患者未发生心律失常,而2岁及以上的患者中有24例发生心律失常(P = 0.0001)。气道通过面罩管理的老年患者的发生率(13.2%[159例患者中的21例])高于气管插管患者(3.3%[90例患者中的3例])(P = 0.01)。在气管插管的老年患者中,20次高碳酸血症发作中有1次高碳酸血症与心律失常相关。气道通过面罩管理的16例高碳酸血症患者中有7例发生心律失常(P = 0.0014);8例中,心律失常与浅麻醉相关;7例中,心律失常与高碳酸血症或浅麻醉均无关。55名2岁及以上气道通过面罩管理且正在接受睾丸固定术或疝修补术的患者中有13例发生心律失常,而30名气管插管患者中有1例发生心律失常(P = 0.016)。与所有其他技术相比,氟烷麻醉期间心律失常的发生率更高(P = 0.035)。作者得出结论,2岁以下婴儿心律失常的发生率极低。高碳酸血症与气道通过面罩管理的儿科患者的心律失常相关,但与气管插管患者无关。(摘要截短至250字)